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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PANX1
All Species:
4.85
Human Site:
T408
Identified Species:
13.33
UniProt:
Q96RD7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RD7
NP_056183.2
426
48059
T408
G
M
N
I
D
S
E
T
K
A
N
N
G
E
K
Chimpanzee
Pan troglodytes
XP_522150
426
48087
T408
A
M
N
I
D
S
E
T
K
A
N
N
G
E
K
Rhesus Macaque
Macaca mulatta
XP_001088479
426
47923
I408
D
M
N
I
D
S
E
I
K
A
N
N
G
K
K
Dog
Lupus familis
XP_849329
426
47856
E407
K
D
S
N
V
P
S
E
T
K
V
N
N
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIP4
426
48234
E407
K
D
L
D
L
S
S
E
A
R
A
N
N
G
E
Rat
Rattus norvegicus
P60570
426
48055
E407
K
D
L
D
L
S
S
E
T
A
A
N
N
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513293
535
58984
S476
L
K
A
A
P
Q
L
S
T
A
T
F
L
F
G
Chicken
Gallus gallus
XP_001235339
356
40359
A340
P
G
K
P
E
E
T
A
V
E
E
L
E
K
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957210
417
46937
E400
E
F
A
P
L
L
P
E
D
C
L
R
K
H
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.7
84.5
N.A.
86.6
88.2
N.A.
58.5
57.9
N.A.
56.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.5
90.8
N.A.
95
95.3
N.A.
66.1
67.8
N.A.
73.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
80
6.6
N.A.
13.3
20
N.A.
6.6
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
86.6
20
N.A.
20
26.6
N.A.
13.3
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
23
12
0
0
0
12
12
56
23
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
12
34
0
23
34
0
0
0
12
0
0
0
0
0
12
% D
% Glu:
12
0
0
0
12
12
34
45
0
12
12
0
12
23
45
% E
% Phe:
0
12
0
0
0
0
0
0
0
0
0
12
0
12
0
% F
% Gly:
12
12
0
0
0
0
0
0
0
0
0
0
34
34
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
0
34
0
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
34
12
12
0
0
0
0
0
34
12
0
0
12
23
34
% K
% Leu:
12
0
23
0
34
12
12
0
0
0
12
12
12
0
0
% L
% Met:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
34
12
0
0
0
0
0
0
34
67
34
0
0
% N
% Pro:
12
0
0
23
12
12
12
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
0
12
0
0
0
% R
% Ser:
0
0
12
0
0
56
34
12
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
12
23
34
0
12
0
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
12
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _