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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HHIP All Species: 27.58
Human Site: S57 Identified Species: 60.67
UniProt: Q96QV1 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96QV1 NP_071920.1 700 78851 S57 R R D R R M M S Q L E L L S G
Chimpanzee Pan troglodytes XP_001146476 700 78743 S57 R R D R R M M S Q L E L L S G
Rhesus Macaque Macaca mulatta XP_001093950 700 78823 S57 R R D R R M M S Q L E L L S G
Dog Lupus familis XP_532677 700 78841 S57 R R D R R L M S Q L E L L S G
Cat Felis silvestris
Mouse Mus musculus Q7TN16 700 78494 S57 R R D R R V M S Q L E L L S G
Rat Rattus norvegicus XP_238042 700 78564 S57 R R D R R M M S Q L E L L S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513389 854 96306 S208 R R D R R V M S Q L E A P S G
Chicken Gallus gallus XP_420424 1391 151286 L747 K K R D R R L L S P E A P G G
Frog Xenopus laevis NP_001080405 696 78254 K54 R V K K R H R K L Q T L D L G
Zebra Danio Brachydanio rerio NP_001073481 693 78207 L53 L K K K E R K L S L E G S G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794447 1074 120429 S37 Y P P F E L P S D S Q P F C D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.5 96.5 N.A. 94.2 94.1 N.A. 72.8 43.9 78.5 67.5 N.A. N.A. N.A. N.A. 21
Protein Similarity: 100 99.7 99.5 98.7 N.A. 97.2 97.4 N.A. 76.9 47.9 88.7 79.7 N.A. N.A. N.A. N.A. 34.3
P-Site Identity: 100 100 100 93.3 N.A. 93.3 100 N.A. 80 20 26.6 20 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 40 33.3 33.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 64 10 0 0 0 0 10 0 0 0 10 0 10 % D
% Glu: 0 0 0 0 19 0 0 0 0 0 82 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 10 0 19 91 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 19 19 19 0 0 10 10 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 19 10 19 10 73 0 64 55 10 0 % L
% Met: 0 0 0 0 0 37 64 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 10 0 0 0 10 0 0 10 0 10 19 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 64 10 10 0 0 0 0 % Q
% Arg: 73 64 10 64 82 19 10 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 73 19 10 0 0 10 64 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % T
% Val: 0 10 0 0 0 19 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _