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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARX
All Species:
18.79
Human Site:
S452
Identified Species:
31.79
UniProt:
Q96QS3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96QS3
NP_620689.1
562
58160
S452
P
P
P
P
G
S
A
S
L
P
P
S
G
A
P
Chimpanzee
Pan troglodytes
XP_521895
295
32253
Q186
T
R
A
E
N
Y
A
Q
I
Q
N
P
S
W
L
Rhesus Macaque
Macaca mulatta
XP_001091313
562
58114
S452
P
P
P
P
G
S
A
S
L
P
P
S
G
A
P
Dog
Lupus familis
XP_859978
564
58517
S454
P
P
P
P
G
S
A
S
L
P
P
S
G
A
P
Cat
Felis silvestris
Mouse
Mus musculus
O35085
564
58472
S454
P
P
P
P
G
S
A
S
L
P
P
S
G
A
P
Rat
Rattus norvegicus
A6YP92
566
58628
S456
P
P
P
P
G
S
A
S
L
P
P
S
G
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513317
245
26769
L137
L
P
L
S
T
M
P
L
P
P
V
T
P
A
F
Chicken
Gallus gallus
Q9PVY0
228
25826
N120
N
R
P
P
M
T
A
N
V
G
P
M
S
N
S
Frog
Xenopus laevis
Q91574
335
37508
Y227
V
L
P
R
A
D
S
Y
P
Q
I
Q
N
N
L
Zebra Danio
Brachydanio rerio
O42115
453
49378
P345
S
A
L
P
P
A
T
P
L
G
L
G
T
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q06453
408
43639
P300
Q
H
P
T
A
H
P
P
P
P
Q
A
P
P
Q
Honey Bee
Apis mellifera
XP_624630
369
40270
G261
A
F
R
Y
P
P
L
G
H
G
P
V
L
P
G
Nematode Worm
Caenorhab. elegans
P29506
252
28335
R144
Q
N
R
R
A
K
W
R
K
R
E
Q
N
R
N
Sea Urchin
Strong. purpuratus
Q26657
327
37128
F219
Q
R
R
Y
R
T
T
F
T
S
Y
Q
L
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.5
99.2
88.1
N.A.
95.7
95.5
N.A.
25.6
20.8
25.4
58.5
N.A.
21
27.5
20.8
25.2
Protein Similarity:
100
32.2
99.4
89.1
N.A.
96.2
95.9
N.A.
32
27.3
34.8
66.5
N.A.
32.3
37.3
27.9
34.7
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
20
26.6
6.6
13.3
N.A.
13.3
6.6
0
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
26.6
46.6
13.3
20
N.A.
20
6.6
0
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
22
8
50
0
0
0
0
8
0
43
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
8
0
0
8
8
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
8
% F
% Gly:
0
0
0
0
36
0
0
8
0
22
0
8
36
0
8
% G
% His:
0
8
0
0
0
8
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% K
% Leu:
8
8
15
0
0
0
8
8
43
0
8
0
15
0
22
% L
% Met:
0
0
0
0
8
8
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
8
0
0
8
0
0
8
0
0
8
0
15
15
8
% N
% Pro:
36
43
58
50
15
8
15
15
22
50
50
8
15
15
36
% P
% Gln:
22
0
0
0
0
0
0
8
0
15
8
22
0
0
8
% Q
% Arg:
0
22
22
15
8
0
0
8
0
8
0
0
0
8
0
% R
% Ser:
8
0
0
8
0
36
8
36
0
8
0
36
15
0
8
% S
% Thr:
8
0
0
8
8
15
15
0
8
0
0
8
8
0
0
% T
% Val:
8
0
0
0
0
0
0
0
8
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
15
0
8
0
8
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _