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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PURB All Species: 33.33
Human Site: T149 Identified Species: 73.33
UniProt: Q96QR8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96QR8 NP_150093.1 312 33241 T149 R F L R I R Q T V N R G G G G
Chimpanzee Pan troglodytes XP_001136727 295 32969 T146 R F L R I R Q T V N R G P G L
Rhesus Macaque Macaca mulatta XP_001085613 304 33781 T155 R F L R I R Q T V N R G P G L
Dog Lupus familis XP_850017 341 36742 T187 R F L R I R Q T V N R G G G G
Cat Felis silvestris
Mouse Mus musculus O35295 324 33883 T161 R F L R I R Q T V N R G G G G
Rat Rattus norvegicus Q68A21 315 33399 T152 R F L R I R Q T V N R G G G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426295 336 38538 T190 R F L R I R Q T M S R G P G M
Frog Xenopus laevis Q8AVS4 328 34968 T153 R F L R I R Q T I N R G P G F
Zebra Danio Brachydanio rerio Q6PHK6 297 32588 T145 R F L R I R Q T V N R G P G F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784262 259 29404 N118 S E V I V K E N R R Y Y L D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SKZ1 296 32182 I151 G W A A F R N I L A E I H E A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.5 70.5 82.1 N.A. 94.4 97.1 N.A. N.A. 51.4 81.7 83 N.A. N.A. N.A. N.A. 45.8
Protein Similarity: 100 79.1 79.1 83.5 N.A. 95.3 97.4 N.A. N.A. 64.2 86.2 87.8 N.A. N.A. N.A. N.A. 62.1
P-Site Identity: 100 86.6 86.6 100 N.A. 100 100 N.A. N.A. 73.3 80 86.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 86.6 86.6 100 N.A. 100 100 N.A. N.A. 86.6 86.6 86.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 26.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 0 0 0 0 10 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 10 0 0 0 0 10 0 0 0 10 0 0 10 0 % E
% Phe: 0 82 0 0 10 0 0 0 0 0 0 0 0 0 19 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 82 37 82 37 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 10 82 0 0 10 10 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 82 0 0 0 0 0 10 0 0 0 10 0 28 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 10 10 0 73 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 46 0 0 % P
% Gln: 0 0 0 0 0 0 82 0 0 0 0 0 0 0 0 % Q
% Arg: 82 0 0 82 0 91 0 0 10 10 82 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 82 0 0 0 0 0 0 0 % T
% Val: 0 0 10 0 10 0 0 0 64 0 0 0 0 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _