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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS35
All Species:
30.42
Human Site:
Y791
Identified Species:
74.36
UniProt:
Q96QK1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96QK1
NP_060676.2
796
91707
Y791
P
E
S
E
G
P
I
Y
E
G
L
I
L
_
_
Chimpanzee
Pan troglodytes
XP_001161357
757
87158
Y752
P
E
S
E
G
P
I
Y
E
G
L
I
L
_
_
Rhesus Macaque
Macaca mulatta
XP_001108828
723
82177
Y718
P
E
S
E
G
P
I
Y
E
G
L
I
L
_
_
Dog
Lupus familis
XP_532570
729
83927
Y724
P
E
S
E
G
P
I
Y
E
G
L
V
L
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQH3
796
91694
Y791
P
E
S
E
G
P
I
Y
E
G
L
I
L
_
_
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520331
455
52644
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089981
796
91412
Y791
P
E
G
D
G
P
I
Y
E
G
L
V
L
_
_
Zebra Danio
Brachydanio rerio
NP_001020688
831
95262
Y826
P
E
S
E
G
P
A
Y
E
G
L
V
L
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392327
805
92283
Y800
P
E
A
D
G
V
S
Y
Q
G
L
V
L
_
_
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34110
944
109124
D936
I
E
S
Q
R
E
V
D
D
R
F
K
V
I
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
84.6
91.3
N.A.
99.3
N.A.
N.A.
56.5
N.A.
94.5
90
N.A.
N.A.
69
N.A.
N.A.
Protein Similarity:
100
95
84.6
91.5
N.A.
99.8
N.A.
N.A.
57.1
N.A.
97.6
93.6
N.A.
N.A.
83.9
N.A.
N.A.
P-Site Identity:
100
100
100
92.3
N.A.
100
N.A.
N.A.
0
N.A.
76.9
84.6
N.A.
N.A.
53.8
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
0
N.A.
92.3
92.3
N.A.
N.A.
84.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
20
0
0
0
10
10
0
0
0
0
0
0
% D
% Glu:
0
90
0
60
0
10
0
0
70
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
10
0
80
0
0
0
0
80
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
60
0
0
0
0
40
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
80
0
80
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
80
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
70
0
0
0
10
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
10
0
0
0
0
40
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
80
% _