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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS35
All Species:
31.82
Human Site:
T739
Identified Species:
77.78
UniProt:
Q96QK1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96QK1
NP_060676.2
796
91707
T739
E
K
E
N
D
A
V
T
I
Q
V
L
N
Q
L
Chimpanzee
Pan troglodytes
XP_001161357
757
87158
T700
E
K
E
N
D
A
V
T
I
Q
V
L
N
Q
L
Rhesus Macaque
Macaca mulatta
XP_001108828
723
82177
T666
E
K
E
N
D
A
V
T
I
Q
V
L
N
Q
L
Dog
Lupus familis
XP_532570
729
83927
T672
E
K
E
N
D
A
V
T
I
Q
V
L
N
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQH3
796
91694
T739
E
K
E
N
D
A
V
T
I
Q
V
L
N
Q
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520331
455
52644
P404
L
T
R
L
L
K
I
P
V
D
T
Y
N
N
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089981
796
91412
T739
E
K
E
N
D
G
V
T
V
Q
V
L
N
Q
L
Zebra Danio
Brachydanio rerio
NP_001020688
831
95262
T774
E
R
E
N
D
A
V
T
V
Q
V
L
N
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392327
805
92283
T748
E
K
G
N
T
M
F
T
V
D
I
I
N
Q
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34110
944
109124
T812
I
H
G
D
E
S
E
T
H
I
S
I
K
Y
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
84.6
91.3
N.A.
99.3
N.A.
N.A.
56.5
N.A.
94.5
90
N.A.
N.A.
69
N.A.
N.A.
Protein Similarity:
100
95
84.6
91.5
N.A.
99.8
N.A.
N.A.
57.1
N.A.
97.6
93.6
N.A.
N.A.
83.9
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
6.6
N.A.
86.6
86.6
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
26.6
N.A.
93.3
100
N.A.
N.A.
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
70
0
0
0
0
20
0
0
0
0
0
% D
% Glu:
80
0
70
0
10
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
20
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
0
50
10
10
20
0
0
20
% I
% Lys:
0
70
0
0
0
10
0
0
0
0
0
0
10
0
0
% K
% Leu:
10
0
0
10
10
0
0
0
0
0
0
70
0
0
70
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
80
0
0
0
0
0
0
0
0
90
10
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
70
0
0
0
80
0
% Q
% Arg:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% S
% Thr:
0
10
0
0
10
0
0
90
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
70
0
40
0
70
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _