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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS35
All Species:
22.42
Human Site:
S437
Identified Species:
54.81
UniProt:
Q96QK1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96QK1
NP_060676.2
796
91707
S437
Y
E
S
R
K
S
M
S
C
Y
V
L
S
N
V
Chimpanzee
Pan troglodytes
XP_001161357
757
87158
S398
Y
E
S
R
K
S
M
S
C
Y
V
L
S
N
V
Rhesus Macaque
Macaca mulatta
XP_001108828
723
82177
F372
E
Q
S
L
V
G
R
F
I
H
L
L
R
S
E
Dog
Lupus familis
XP_532570
729
83927
S370
Y
E
S
R
K
S
M
S
C
Y
V
L
S
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQH3
796
91694
S437
Y
E
S
R
K
S
M
S
C
Y
V
L
S
N
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520331
455
52644
R144
R
G
V
Q
H
P
L
R
G
L
F
L
R
N
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089981
796
91412
S437
Y
E
S
R
K
S
M
S
C
Y
V
L
S
N
A
Zebra Danio
Brachydanio rerio
NP_001020688
831
95262
S472
Y
E
S
R
K
S
M
S
C
Y
V
L
S
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392327
805
92283
A446
Y
E
G
R
K
L
L
A
I
Y
I
I
T
N
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34110
944
109124
A425
Q
L
I
S
Q
C
Q
A
Y
K
N
I
L
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
84.6
91.3
N.A.
99.3
N.A.
N.A.
56.5
N.A.
94.5
90
N.A.
N.A.
69
N.A.
N.A.
Protein Similarity:
100
95
84.6
91.5
N.A.
99.8
N.A.
N.A.
57.1
N.A.
97.6
93.6
N.A.
N.A.
83.9
N.A.
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
N.A.
N.A.
13.3
N.A.
93.3
93.3
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
100
100
40
100
N.A.
100
N.A.
N.A.
26.6
N.A.
93.3
100
N.A.
N.A.
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
20
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
10
0
0
60
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
70
0
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% F
% Gly:
0
10
10
0
0
10
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
20
0
10
20
0
0
20
% I
% Lys:
0
0
0
0
70
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
10
0
10
0
10
20
0
0
10
10
80
10
0
10
% L
% Met:
0
0
0
0
0
0
60
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
80
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
0
10
10
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
70
0
0
10
10
0
0
0
0
20
0
0
% R
% Ser:
0
0
70
10
0
60
0
60
0
0
0
0
60
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
10
0
10
0
0
0
0
0
60
0
0
0
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
70
0
0
0
0
0
0
0
10
70
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _