Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEDD4L All Species: 25.45
Human Site: T318 Identified Species: 46.67
UniProt: Q96PU5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96PU5 NP_001138436.1 975 111932 T318 L S R R L Q I T P D S N G E Q
Chimpanzee Pan troglodytes XP_001140254 911 104904 T318 L S R R L Q I T P D S N G E Q
Rhesus Macaque Macaca mulatta XP_001088661 1010 115306 T353 L S R R L Q I T P D S N G E Q
Dog Lupus familis XP_533393 1027 117927 T370 L S R R L Q I T P D S N G E Q
Cat Felis silvestris
Mouse Mus musculus Q8CFI0 1004 115400 T347 V S R R L Q I T P D S N G E Q
Rat Rattus norvegicus Q62940 887 102376 P312 I S E D V D G P D N H E S P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511197 1255 141275 S478 N V P C C L S S L K Y N C S K
Chicken Gallus gallus XP_424462 1045 119140 T388 L S R R L Q I T P D S N G E Q
Frog Xenopus laevis Q2TAS2 751 86306 S196 T R P A S E Y S S P G R P L S
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 T210 S C L V D E N T P I M T P N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVI3 1007 114856 I357 N N G I L A Q I A M Q Y R A E
Honey Bee Apis mellifera XP_395191 782 90150 A226 W E R P T E S A N M T I E R N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39940 809 91798 T254 Y V D H N T R T T T W K R P T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.4 92.4 90.8 N.A. 94.3 48 N.A. 43.9 85.6 34.1 34.3 N.A. 47.2 49.4 N.A. N.A.
Protein Similarity: 100 93.4 93.7 92.2 N.A. 95.6 60 N.A. 54 88.4 49 49.5 N.A. 61.8 61.1 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 6.6 N.A. 6.6 100 0 13.3 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 33.3 N.A. 20 100 13.3 20 N.A. 20 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 37 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 52.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 0 8 8 0 0 0 0 8 0 % A
% Cys: 0 8 0 8 8 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 8 8 8 8 0 0 8 47 0 0 0 0 0 % D
% Glu: 0 8 8 0 0 24 0 0 0 0 0 8 8 47 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 8 0 0 0 8 0 47 0 8 % G
% His: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 8 0 0 8 0 0 47 8 0 8 0 8 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 8 % K
% Leu: 39 0 8 0 54 8 0 0 8 0 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 16 8 0 0 0 0 % M
% Asn: 16 8 0 0 8 0 8 0 8 8 0 54 0 8 8 % N
% Pro: 0 0 16 8 0 0 0 8 54 8 0 0 16 16 0 % P
% Gln: 0 0 0 0 0 47 8 0 0 0 8 0 0 0 47 % Q
% Arg: 0 8 54 47 0 0 8 0 0 0 0 8 16 8 0 % R
% Ser: 8 54 0 0 8 0 16 16 8 0 47 0 8 8 8 % S
% Thr: 8 0 0 0 8 8 0 62 8 8 8 8 0 0 8 % T
% Val: 8 16 0 8 8 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 8 0 0 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _