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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEDD4L
All Species:
22.73
Human Site:
T121
Identified Species:
41.67
UniProt:
Q96PU5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PU5
NP_001138436.1
975
111932
T121
H
L
P
T
E
D
P
T
M
E
R
P
Y
T
F
Chimpanzee
Pan troglodytes
XP_001140254
911
104904
T121
H
L
P
T
E
D
P
T
M
E
R
P
Y
T
F
Rhesus Macaque
Macaca mulatta
XP_001088661
1010
115306
T152
H
L
P
T
E
D
P
T
M
E
R
P
Y
T
F
Dog
Lupus familis
XP_533393
1027
117927
T173
H
L
P
T
E
D
P
T
M
E
R
P
Y
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFI0
1004
115400
T149
H
L
P
T
E
D
P
T
M
E
R
P
Y
T
F
Rat
Rattus norvegicus
Q62940
887
102376
L124
T
K
T
I
K
K
S
L
N
P
K
W
N
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511197
1255
141275
L195
S
D
S
G
G
R
T
L
P
R
G
D
G
S
L
Chicken
Gallus gallus
XP_424462
1045
119140
S191
H
L
P
T
E
D
P
S
M
E
R
P
Y
T
F
Frog
Xenopus laevis
Q2TAS2
751
86306
V12
G
S
R
R
N
G
P
V
K
L
R
L
T
V
L
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
K26
L
C
A
K
N
L
V
K
K
D
F
F
R
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
G171
N
L
P
T
E
Q
E
G
R
T
I
G
E
Q
S
Honey Bee
Apis mellifera
XP_395191
782
90150
I42
H
Q
L
A
K
K
D
I
F
G
A
S
D
P
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
V70
N
S
I
L
T
I
Q
V
F
D
Q
K
K
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
92.4
90.8
N.A.
94.3
48
N.A.
43.9
85.6
34.1
34.3
N.A.
47.2
49.4
N.A.
N.A.
Protein Similarity:
100
93.4
93.7
92.2
N.A.
95.6
60
N.A.
54
88.4
49
49.5
N.A.
61.8
61.1
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
0
93.3
13.3
0
N.A.
26.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
6.6
100
13.3
6.6
N.A.
33.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
47
8
0
0
16
0
8
8
0
0
% D
% Glu:
0
0
0
0
54
0
8
0
0
47
0
0
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
16
0
8
8
0
8
47
% F
% Gly:
8
0
0
8
8
8
0
8
0
8
8
8
8
0
0
% G
% His:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
8
0
8
0
0
8
0
0
0
0
% I
% Lys:
0
8
0
8
16
16
0
8
16
0
8
8
8
0
8
% K
% Leu:
8
54
8
8
0
8
0
16
0
8
0
8
0
8
16
% L
% Met:
0
0
0
0
0
0
0
0
47
0
0
0
0
0
0
% M
% Asn:
16
0
0
0
16
0
0
0
8
0
0
0
8
0
0
% N
% Pro:
0
0
54
0
0
0
54
0
8
8
0
47
0
8
8
% P
% Gln:
0
8
0
0
0
8
8
0
0
0
8
0
0
8
0
% Q
% Arg:
0
0
8
8
0
8
0
0
8
8
54
0
8
0
0
% R
% Ser:
8
16
8
0
0
0
8
8
0
0
0
8
0
8
8
% S
% Thr:
8
0
8
54
8
0
8
39
0
8
0
0
8
47
0
% T
% Val:
0
0
0
0
0
0
8
16
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
47
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _