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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEDD4L
All Species:
18.48
Human Site:
S179
Identified Species:
33.89
UniProt:
Q96PU5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PU5
NP_001138436.1
975
111932
S179
H
G
W
E
V
V
D
S
N
D
S
A
S
Q
H
Chimpanzee
Pan troglodytes
XP_001140254
911
104904
S179
H
G
W
E
V
V
D
S
N
D
S
A
S
Q
H
Rhesus Macaque
Macaca mulatta
XP_001088661
1010
115306
E210
F
I
P
Q
H
G
W
E
V
V
D
S
N
D
S
Dog
Lupus familis
XP_533393
1027
117927
S231
H
G
W
E
V
V
D
S
N
D
S
A
S
Q
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFI0
1004
115400
S207
H
G
W
E
V
V
D
S
N
D
S
A
S
Q
H
Rat
Rattus norvegicus
Q62940
887
102376
F182
R
M
E
R
P
Y
T
F
K
D
F
V
L
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511197
1255
141275
P253
A
I
E
N
A
K
S
P
A
R
T
K
S
K
I
Chicken
Gallus gallus
XP_424462
1045
119140
S249
H
G
W
D
V
V
D
S
S
D
S
A
S
Q
R
Frog
Xenopus laevis
Q2TAS2
751
86306
G70
Q
H
Y
D
L
Y
I
G
K
S
D
S
I
T
I
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
K84
I
S
V
W
N
H
K
K
I
H
K
K
Q
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
N229
W
E
H
V
E
A
T
N
A
G
E
T
S
A
Q
Honey Bee
Apis mellifera
XP_395191
782
90150
D100
K
L
V
L
Q
V
F
D
E
N
R
L
T
R
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
S128
S
N
D
G
M
A
V
S
G
R
L
I
V
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
92.4
90.8
N.A.
94.3
48
N.A.
43.9
85.6
34.1
34.3
N.A.
47.2
49.4
N.A.
N.A.
Protein Similarity:
100
93.4
93.7
92.2
N.A.
95.6
60
N.A.
54
88.4
49
49.5
N.A.
61.8
61.1
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
6.6
N.A.
6.6
80
0
0
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
6.6
N.A.
20
93.3
26.6
0
N.A.
13.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
16
0
0
16
0
0
39
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
16
0
0
39
8
0
47
16
0
0
8
8
% D
% Glu:
0
8
16
31
8
0
0
8
8
0
8
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
8
8
0
0
8
0
0
0
0
% F
% Gly:
0
39
0
8
0
8
0
8
8
8
0
0
0
8
0
% G
% His:
39
8
8
0
8
8
0
0
0
8
0
0
0
8
31
% H
% Ile:
8
16
0
0
0
0
8
0
8
0
0
8
8
0
16
% I
% Lys:
8
0
0
0
0
8
8
8
16
0
8
16
0
8
0
% K
% Leu:
0
8
0
8
8
0
0
0
0
0
8
8
8
0
8
% L
% Met:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
8
0
0
8
31
8
0
0
8
0
0
% N
% Pro:
0
0
8
0
8
0
0
8
0
0
0
0
0
0
8
% P
% Gln:
8
0
0
8
8
0
0
0
0
0
0
0
8
39
8
% Q
% Arg:
8
0
0
8
0
0
0
0
0
16
8
0
0
8
8
% R
% Ser:
8
8
0
0
0
0
8
47
8
8
39
16
54
0
8
% S
% Thr:
0
0
0
0
0
0
16
0
0
0
8
8
8
8
0
% T
% Val:
0
0
16
8
39
47
8
0
8
8
0
8
8
8
0
% V
% Trp:
8
0
39
8
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
16
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _