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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIGLEC12
All Species:
4.55
Human Site:
Y577
Identified Species:
20
UniProt:
Q96PQ1
Number Species:
5
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PQ1
NP_201586.1
595
64984
Y577
F
H
K
A
R
P
Q
Y
P
Q
E
Q
E
A
I
Chimpanzee
Pan troglodytes
Q95LH0
597
65057
Y579
F
H
K
A
R
P
Q
Y
P
Q
E
Q
E
A
I
Rhesus Macaque
Macaca mulatta
XP_001116358
596
65528
D578
F
H
K
V
R
P
Q
D
P
Q
E
E
E
A
T
Dog
Lupus familis
XP_541460
697
77324
I635
V
H
P
A
L
D
T
I
S
Q
D
H
L
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91Y57
467
51871
D450
M
N
L
W
G
Q
Q
D
T
T
T
E
Y
S
E
Rat
Rattus norvegicus
NP_001099719
568
62021
K551
G
P
R
P
Q
Q
P
K
N
T
E
T
I
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
83.7
44.3
N.A.
42.6
29.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.8
88
58.2
N.A.
55.2
45.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
73.3
20
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
33.3
N.A.
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
50
0
0
0
0
0
0
0
0
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
17
0
34
0
0
17
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
67
34
50
0
17
% E
% Phe:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
67
0
0
0
0
0
0
0
0
0
17
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
17
0
0
0
0
17
0
34
% I
% Lys:
0
0
50
0
0
0
0
17
0
0
0
0
0
17
17
% K
% Leu:
0
0
17
0
17
0
0
0
0
0
0
0
17
0
0
% L
% Met:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
0
0
0
17
0
0
0
0
0
0
% N
% Pro:
0
17
17
17
0
50
17
0
50
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
17
34
67
0
0
67
0
34
0
0
0
% Q
% Arg:
0
0
17
0
50
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
17
0
0
0
0
34
17
% S
% Thr:
0
0
0
0
0
0
17
0
17
34
17
17
0
0
17
% T
% Val:
17
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _