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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MACF1 All Species: 9.39
Human Site: S374 Identified Species: 25.83
UniProt: Q96PK2 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96PK2 NP_149033.2 5938 670151 S374 P H M Q L A D S A E Q N I N P
Chimpanzee Pan troglodytes XP_001170848 5940 670498 S374 P H M Q L A D S A E Q N I N P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849152 5423 619404 T362 Q Y I H F K E T E I L A K E R
Cat Felis silvestris
Mouse Mus musculus Q9QXZ0 5327 607958 T362 Q Y I H F K E T E I L A K E R
Rat Rattus norvegicus NP_001129230 5430 619582 T362 Q Y I H F K E T E I L A K E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515630 7036 790279 E633 P S V E S Q L E T Q Q H I H T
Chicken Gallus gallus P11533 3660 422863
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920094 5393 611479 T363 E Y V H F K E T E I P A K E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195605 3054 349588
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 68.4 N.A. 64.5 66.6 N.A. 56.2 20.7 N.A. 43.7 N.A. N.A. N.A. N.A. 23.6
Protein Similarity: 100 99.6 N.A. 76.7 N.A. 73.7 75.8 N.A. 67.9 36.3 N.A. 61.7 N.A. N.A. N.A. N.A. 36.2
P-Site Identity: 100 100 N.A. 0 N.A. 0 0 N.A. 20 0 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 N.A. 26.6 N.A. 26.6 26.6 N.A. 53.3 0 N.A. 26.6 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 23 0 0 23 0 0 45 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 % D
% Glu: 12 0 0 12 0 0 45 12 45 23 0 0 0 45 0 % E
% Phe: 0 0 0 0 45 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 23 0 45 0 0 0 0 0 0 0 12 0 12 0 % H
% Ile: 0 0 34 0 0 0 0 0 0 45 0 0 34 0 0 % I
% Lys: 0 0 0 0 0 45 0 0 0 0 0 0 45 0 0 % K
% Leu: 0 0 0 0 23 0 12 0 0 0 34 0 0 0 0 % L
% Met: 0 0 23 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 23 0 23 0 % N
% Pro: 34 0 0 0 0 0 0 0 0 0 12 0 0 0 23 % P
% Gln: 34 0 0 23 0 12 0 0 0 12 34 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 % R
% Ser: 0 12 0 0 12 0 0 23 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 45 12 0 0 0 0 0 12 % T
% Val: 0 0 23 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 45 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _