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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSSK2
All Species:
17.58
Human Site:
Y250
Identified Species:
38.67
UniProt:
Q96PF2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PF2
NP_443732.3
358
40939
Y250
C
E
C
K
D
L
I
Y
R
M
L
Q
P
D
V
Chimpanzee
Pan troglodytes
XP_001165103
358
40919
Y250
C
E
C
K
D
L
I
Y
R
M
L
Q
P
D
V
Rhesus Macaque
Macaca mulatta
XP_001104572
362
41389
Y250
C
E
C
K
D
L
I
Y
R
M
L
Q
P
D
V
Dog
Lupus familis
XP_543552
358
40929
Y250
G
E
C
K
D
L
I
Y
R
M
L
Q
P
D
V
Cat
Felis silvestris
Mouse
Mus musculus
O54863
357
40661
Y249
G
E
C
K
D
L
I
Y
R
I
L
Q
P
D
V
Rat
Rattus norvegicus
Q9R1U5
776
84890
R256
Q
D
C
E
T
L
I
R
R
M
L
V
V
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518965
347
39229
K246
K
H
L
T
S
E
C
K
D
L
I
Y
R
M
L
Chicken
Gallus gallus
Q9IA88
798
88848
R255
E
D
C
E
T
L
I
R
R
M
L
V
V
D
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
H317
R
P
I
V
N
L
L
H
H
M
L
C
V
D
P
Sea Urchin
Strong. purpuratus
XP_787834
432
48308
L270
L
L
F
K
D
I
V
L
A
I
L
Q
P
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
P250
S
E
A
R
D
L
I
P
R
M
L
I
V
D
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.1
93.8
N.A.
90.2
20.8
N.A.
77.6
20.5
N.A.
N.A.
N.A.
N.A.
N.A.
20.6
37.7
Protein Similarity:
100
99.4
97.7
97.4
N.A.
94.4
32.2
N.A.
86
30.7
N.A.
N.A.
N.A.
N.A.
N.A.
34.9
55
P-Site Identity:
100
100
100
93.3
N.A.
86.6
46.6
N.A.
0
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
33.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
60
N.A.
20
60
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
10
% A
% Cys:
28
0
64
0
0
0
10
0
0
0
0
10
0
0
0
% C
% Asp:
0
19
0
0
64
0
0
0
10
0
0
0
0
82
0
% D
% Glu:
10
55
0
19
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
10
10
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
10
73
0
0
19
10
10
0
0
0
% I
% Lys:
10
0
0
55
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
10
10
10
0
0
82
10
10
0
10
91
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
73
0
0
0
10
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
10
0
0
0
0
55
0
37
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% Q
% Arg:
10
0
0
10
0
0
0
19
73
0
0
0
10
0
0
% R
% Ser:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
10
19
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
10
0
0
0
0
19
37
0
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
46
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _