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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDFY2
All Species:
39.39
Human Site:
S218
Identified Species:
72.22
UniProt:
Q96P53
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96P53
NP_443182.1
400
45154
S218
Q
R
V
L
F
S
G
S
S
D
H
S
V
I
M
Chimpanzee
Pan troglodytes
XP_001158979
400
45122
S218
Q
R
V
L
F
S
G
S
S
D
H
S
V
I
M
Rhesus Macaque
Macaca mulatta
XP_001106117
400
45142
S218
Q
R
V
L
F
S
G
S
S
D
H
S
V
I
M
Dog
Lupus familis
XP_848495
524
57749
S342
Q
R
V
L
F
S
G
S
S
D
H
S
V
I
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUB4
400
45028
S218
Q
R
V
L
F
S
G
S
S
D
H
S
V
I
M
Rat
Rattus norvegicus
NP_001100739
327
36827
K159
M
W
D
I
G
G
R
K
G
T
A
I
E
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513414
461
52320
S279
Q
R
M
L
F
S
G
S
S
D
H
S
I
I
M
Chicken
Gallus gallus
NP_001073218
400
44983
S218
Q
R
V
L
F
S
G
S
S
D
H
S
I
I
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_991308
400
45108
S218
Q
R
V
L
F
S
G
S
S
D
H
S
I
I
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609400
408
46172
A226
P
Q
L
L
F
S
G
A
C
D
Q
S
V
L
V
Honey Bee
Apis mellifera
XP_393586
408
45790
S226
K
Q
L
L
F
S
G
S
F
D
Q
S
I
I
V
Nematode Worm
Caenorhab. elegans
Q18964
415
46221
D225
V
L
Y
S
G
S
S
D
H
L
I
I
M
W
D
Sea Urchin
Strong. purpuratus
XP_795599
403
45569
S221
R
K
L
L
F
S
G
S
F
D
Q
S
I
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
69.8
N.A.
98
80.2
N.A.
73.3
92.5
N.A.
84.2
N.A.
49.7
54.1
40
58.5
Protein Similarity:
100
100
99.5
72.9
N.A.
99.7
81.7
N.A.
81.3
96.7
N.A.
93.2
N.A.
73.2
73.2
59.7
76.6
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
86.6
93.3
N.A.
93.3
N.A.
46.6
53.3
6.6
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
100
N.A.
100
N.A.
80
86.6
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
8
0
85
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
85
0
0
0
16
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
16
8
85
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
62
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
8
16
39
77
0
% I
% Lys:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
8
24
85
0
0
0
0
0
8
0
0
0
16
0
% L
% Met:
8
0
8
0
0
0
0
0
0
0
0
0
8
0
62
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
62
16
0
0
0
0
0
0
0
0
24
0
0
0
8
% Q
% Arg:
8
62
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
0
93
8
77
62
0
0
85
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
8
0
54
0
0
0
0
0
0
0
0
0
47
0
16
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _