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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NSUN5 All Species: 17.27
Human Site: S132 Identified Species: 25.33
UniProt: Q96P11 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96P11 NP_060514.1 429 46692 S132 G S R P G P A S Q L P R F V R
Chimpanzee Pan troglodytes XP_519138 437 47282 S132 G S R P G P A S Q L P R F V R
Rhesus Macaque Macaca mulatta XP_001110692 429 46730 S132 G S R P G P V S Q L P R F V R
Dog Lupus familis XP_536846 469 51185 S132 G S R P G A A S Q V P R F V R
Cat Felis silvestris
Mouse Mus musculus Q8K4F6 465 51011 Y132 S S R P G Q A Y Q V P R F V R
Rat Rattus norvegicus XP_213749 451 49532 H130 Q E R P G Q A H Q V P R F V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514526 433 47383 T113 V R V N T L K T C P G D A V D
Chicken Gallus gallus XP_415710 465 50976 P132 S G A G P E A P Q V P R Y V R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998450 435 49024 D130 S I Q Q T Q N D V I P R Y V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393743 578 66348 V217 A L H E P D N V K N A R Y V R
Nematode Worm Caenorhab. elegans NP_497089 439 49820 I136 A D D G M K K I Q I P R Y A R
Sea Urchin Strong. purpuratus XP_787860 508 56859 V138 P S Q V K D E V S I P R Y I R
Poplar Tree Populus trichocarpa XP_002309481 433 47775 R139 A L A K L V V R K K A K N I D
Maize Zea mays NP_001151492 498 55261 R157 T L D K V C A R K R V R C V E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_851079 567 63156 R212 G L A T L L V R K K V D S V D
Baker's Yeast Sacchar. cerevisiae P53972 490 56159 V153 I S N D L P P V R W I R I N P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.4 96.9 81.2 N.A. 81.7 83.8 N.A. 73.4 61 N.A. 57.9 N.A. N.A. 29.2 35.7 38.9
Protein Similarity: 100 90.6 98.5 85.7 N.A. 86.2 88.6 N.A. 80.1 72.9 N.A. 71 N.A. N.A. 43.5 55.1 55.3
P-Site Identity: 100 100 93.3 86.6 N.A. 73.3 66.6 N.A. 6.6 40 N.A. 26.6 N.A. N.A. 20 26.6 26.6
P-Site Similarity: 100 100 93.3 93.3 N.A. 80 73.3 N.A. 13.3 53.3 N.A. 46.6 N.A. N.A. 33.3 40 53.3
Percent
Protein Identity: 33.2 30.7 N.A. 28.9 28.5 N.A.
Protein Similarity: 50.3 44.3 N.A. 42.1 48.3 N.A.
P-Site Identity: 0 20 N.A. 13.3 20 N.A.
P-Site Similarity: 20 26.6 N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 19 0 0 7 44 0 0 0 13 0 7 7 0 % A
% Cys: 0 0 0 0 0 7 0 0 7 0 0 0 7 0 0 % C
% Asp: 0 7 13 7 0 13 0 7 0 0 0 13 0 0 19 % D
% Glu: 0 7 0 7 0 7 7 0 0 0 0 0 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 38 0 0 % F
% Gly: 32 7 0 13 38 0 0 0 0 0 7 0 0 0 0 % G
% His: 0 0 7 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 7 7 0 0 0 0 0 7 0 19 7 0 7 13 0 % I
% Lys: 0 0 0 13 7 7 13 0 25 13 0 7 0 0 0 % K
% Leu: 0 25 0 0 19 13 0 0 0 19 0 0 0 0 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 7 0 0 13 0 0 7 0 0 7 7 0 % N
% Pro: 7 0 0 38 13 25 7 7 0 7 63 0 0 0 7 % P
% Gln: 7 0 13 7 0 19 0 0 50 0 0 0 0 0 0 % Q
% Arg: 0 7 38 0 0 0 0 19 7 7 0 82 0 0 69 % R
% Ser: 19 44 0 0 0 0 0 25 7 0 0 0 7 0 0 % S
% Thr: 7 0 0 7 13 0 0 7 0 0 0 0 0 0 0 % T
% Val: 7 0 7 7 7 7 19 19 7 25 13 0 0 75 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 0 0 32 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _