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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG8
All Species:
13.64
Human Site:
Y188
Identified Species:
23.08
UniProt:
Q96MW5
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MW5
NP_115758.3
612
68424
Y188
V
R
R
L
E
R
K
Y
S
S
I
P
V
I
Q
Chimpanzee
Pan troglodytes
XP_511064
394
44531
N28
L
M
D
T
C
V
R
N
S
Y
Y
E
E
A
L
Rhesus Macaque
Macaca mulatta
XP_001100394
487
54500
K121
T
E
A
E
L
R
V
K
F
L
Q
A
R
D
A
Dog
Lupus familis
XP_546857
624
69140
Y190
V
R
R
L
E
R
K
Y
S
S
I
P
V
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJA2
640
71600
Y194
V
R
R
L
E
R
K
Y
S
S
I
P
V
I
Q
Rat
Rattus norvegicus
NP_001099652
634
70744
Y194
V
R
R
L
E
R
K
Y
S
S
I
P
V
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510195
500
55836
W133
F
L
Q
A
R
D
A
W
L
R
A
I
L
T
A
Chicken
Gallus gallus
XP_001232975
677
74631
Q182
G
I
V
A
E
V
R
Q
S
T
Q
L
M
L
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013524
634
71570
L175
L
E
K
K
H
S
S
L
P
V
I
Q
G
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKH0
570
64891
Q175
A
T
R
L
G
Q
H
Q
G
H
I
P
V
V
T
Honey Bee
Apis mellifera
XP_623492
605
69076
A180
P
I
I
S
S
I
V
A
E
I
E
S
S
W
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001204069
378
43256
L12
N
P
D
F
A
L
Y
L
T
E
L
S
S
F
G
Poplar Tree
Populus trichocarpa
XP_002308543
575
64166
L188
R
Q
T
T
Q
S
L
L
S
Q
L
L
Q
K
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568256
569
63034
L188
R
Q
T
T
Q
S
L
L
S
Q
L
L
Q
K
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.7
76.9
86.5
N.A.
86
87.6
N.A.
65.3
63.2
N.A.
67
N.A.
41.5
40.6
N.A.
41.1
Protein Similarity:
100
64.2
77.7
90.3
N.A.
89
91
N.A.
70.7
71.7
N.A.
78.7
N.A.
59.1
62
N.A.
51.1
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
0
13.3
N.A.
13.3
N.A.
33.3
0
N.A.
0
P-Site Similarity:
100
20
6.6
100
N.A.
100
100
N.A.
20
40
N.A.
26.6
N.A.
46.6
0
N.A.
13.3
Percent
Protein Identity:
32.3
N.A.
N.A.
32
N.A.
N.A.
Protein Similarity:
49.6
N.A.
N.A.
49.6
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
15
8
0
8
8
0
0
8
8
0
8
15
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
0
8
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
15
0
8
36
0
0
0
8
8
8
8
8
0
0
% E
% Phe:
8
0
0
8
0
0
0
0
8
0
0
0
0
8
0
% F
% Gly:
8
0
0
0
8
0
0
0
8
0
0
0
8
0
8
% G
% His:
0
0
0
0
8
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
15
8
0
0
8
0
0
0
8
43
8
0
36
0
% I
% Lys:
0
0
8
8
0
0
29
8
0
0
0
0
0
15
0
% K
% Leu:
15
8
0
36
8
8
15
29
8
8
22
22
8
8
22
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
8
8
0
0
0
0
0
0
8
0
0
36
0
0
0
% P
% Gln:
0
15
8
0
15
8
0
15
0
15
15
8
15
0
29
% Q
% Arg:
15
29
36
0
8
36
15
0
0
8
0
0
8
0
0
% R
% Ser:
0
0
0
8
8
22
8
0
58
29
0
15
15
0
8
% S
% Thr:
8
8
15
22
0
0
0
0
8
8
0
0
0
8
8
% T
% Val:
29
0
8
0
0
15
15
0
0
8
0
0
36
8
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
8
29
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _