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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG8
All Species:
6.67
Human Site:
T603
Identified Species:
11.28
UniProt:
Q96MW5
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MW5
NP_115758.3
612
68424
T603
P
E
G
G
R
A
E
T
Q
A
E
P
P
S
V
Chimpanzee
Pan troglodytes
XP_511064
394
44531
T386
P
P
A
Q
I
A
Q
T
L
G
K
R
M
K
I
Rhesus Macaque
Macaca mulatta
XP_001100394
487
54500
D479
E
G
G
R
E
E
V
D
A
E
P
P
S
V
G
Dog
Lupus familis
XP_546857
624
69140
A614
P
D
G
D
T
S
P
A
P
Q
P
P
A
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJA2
640
71600
P621
G
E
P
L
P
A
E
P
P
S
E
G
G
G
I
Rat
Rattus norvegicus
NP_001099652
634
70744
P614
E
K
G
E
S
G
E
P
L
P
Q
E
P
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510195
500
55836
L491
E
E
E
E
E
E
P
L
Q
A
D
P
S
A
G
Chicken
Gallus gallus
XP_001232975
677
74631
H577
P
A
A
L
R
R
A
H
R
I
E
P
F
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013524
634
71570
T589
P
E
E
P
V
S
V
T
D
P
Q
K
D
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKH0
570
64891
M556
V
Q
P
Q
D
K
V
M
E
A
K
P
S
A
G
Honey Bee
Apis mellifera
XP_623492
605
69076
S596
N
K
I
L
A
N
N
S
S
A
D
G
E
N
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001204069
378
43256
S370
S
Q
A
F
L
A
M
S
S
V
S
I
P
S
N
Poplar Tree
Populus trichocarpa
XP_002308543
575
64166
K567
P
T
V
Q
I
D
E
K
Q
G
D
S
V
A
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568256
569
63034
I558
K
E
E
D
N
S
P
I
P
L
Q
T
P
E
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.7
76.9
86.5
N.A.
86
87.6
N.A.
65.3
63.2
N.A.
67
N.A.
41.5
40.6
N.A.
41.1
Protein Similarity:
100
64.2
77.7
90.3
N.A.
89
91
N.A.
70.7
71.7
N.A.
78.7
N.A.
59.1
62
N.A.
51.1
P-Site Identity:
100
20
13.3
20
N.A.
26.6
20
N.A.
26.6
26.6
N.A.
26.6
N.A.
13.3
6.6
N.A.
20
P-Site Similarity:
100
40
13.3
40
N.A.
40
33.3
N.A.
40
40
N.A.
40
N.A.
40
33.3
N.A.
33.3
Percent
Protein Identity:
32.3
N.A.
N.A.
32
N.A.
N.A.
Protein Similarity:
49.6
N.A.
N.A.
49.6
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
22
0
8
29
8
8
8
29
0
0
8
29
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
15
8
8
0
8
8
0
22
0
8
8
0
% D
% Glu:
22
36
22
15
15
15
29
0
8
8
22
8
8
8
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
8
29
8
0
8
0
0
0
15
0
15
8
8
22
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
15
0
0
8
0
8
0
8
0
0
22
% I
% Lys:
8
15
0
0
0
8
0
8
0
0
15
8
0
8
0
% K
% Leu:
0
0
0
22
8
0
0
8
15
8
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
8
8
0
0
0
0
8
0
0
% M
% Asn:
8
0
0
0
8
8
8
0
0
0
0
0
0
8
8
% N
% Pro:
43
8
15
8
8
0
22
15
22
15
15
43
29
8
0
% P
% Gln:
0
15
0
22
0
0
8
0
22
8
22
0
0
0
8
% Q
% Arg:
0
0
0
8
15
8
0
0
8
0
0
8
0
0
0
% R
% Ser:
8
0
0
0
8
22
0
15
15
8
8
8
22
15
15
% S
% Thr:
0
8
0
0
8
0
0
22
0
0
0
8
0
0
0
% T
% Val:
8
0
8
0
8
0
22
0
0
8
0
0
8
15
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _