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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG8
All Species:
4.85
Human Site:
T564
Identified Species:
8.21
UniProt:
Q96MW5
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MW5
NP_115758.3
612
68424
T564
P
K
R
E
T
L
F
T
L
D
D
Q
A
L
G
Chimpanzee
Pan troglodytes
XP_511064
394
44531
T360
E
L
F
V
Q
F
C
T
V
F
L
E
D
L
V
Rhesus Macaque
Macaca mulatta
XP_001100394
487
54500
A453
G
P
E
L
T
A
P
A
P
E
P
P
S
E
E
Dog
Lupus familis
XP_546857
624
69140
C566
P
K
R
E
L
V
L
C
L
E
D
K
E
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJA2
640
71600
C570
P
K
R
E
T
V
F
C
L
D
E
Q
E
L
G
Rat
Rattus norvegicus
NP_001099652
634
70744
C570
P
K
R
E
A
V
F
C
L
D
D
Q
E
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510195
500
55836
T465
E
L
P
E
R
E
Q
T
L
E
S
A
G
R
P
Chicken
Gallus gallus
XP_001232975
677
74631
P540
P
A
Q
E
A
E
L
P
P
G
E
E
E
P
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013524
634
71570
P545
P
Q
K
E
P
V
T
P
V
L
D
L
C
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKH0
570
64891
L530
E
Q
Q
Q
L
T
Y
L
Q
Q
T
R
I
L
E
Honey Bee
Apis mellifera
XP_623492
605
69076
I531
P
I
Q
K
N
L
P
I
S
N
V
Q
S
L
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001204069
378
43256
L344
L
H
S
F
L
S
T
L
K
S
A
S
E
R
F
Poplar Tree
Populus trichocarpa
XP_002308543
575
64166
T541
L
V
V
E
N
G
V
T
P
E
V
E
P
S
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568256
569
63034
S532
S
T
D
T
K
D
A
S
E
N
G
V
A
S
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.7
76.9
86.5
N.A.
86
87.6
N.A.
65.3
63.2
N.A.
67
N.A.
41.5
40.6
N.A.
41.1
Protein Similarity:
100
64.2
77.7
90.3
N.A.
89
91
N.A.
70.7
71.7
N.A.
78.7
N.A.
59.1
62
N.A.
51.1
P-Site Identity:
100
13.3
6.6
46.6
N.A.
73.3
66.6
N.A.
20
13.3
N.A.
20
N.A.
6.6
26.6
N.A.
0
P-Site Similarity:
100
26.6
20
66.6
N.A.
86.6
73.3
N.A.
26.6
33.3
N.A.
46.6
N.A.
40
53.3
N.A.
0
Percent
Protein Identity:
32.3
N.A.
N.A.
32
N.A.
N.A.
Protein Similarity:
49.6
N.A.
N.A.
49.6
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
15
8
8
8
0
0
8
8
15
0
8
% A
% Cys:
0
0
0
0
0
0
8
22
0
0
0
0
8
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
0
22
29
0
8
0
8
% D
% Glu:
22
0
8
58
0
15
0
0
8
29
15
22
36
8
15
% E
% Phe:
0
0
8
8
0
8
22
0
0
8
0
0
0
0
8
% F
% Gly:
8
0
0
0
0
8
0
0
0
8
8
0
8
0
22
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
0
0
0
0
8
0
0
% I
% Lys:
0
29
8
8
8
0
0
0
8
0
0
8
0
0
0
% K
% Leu:
15
15
0
8
22
15
15
15
36
8
8
8
0
50
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
15
0
0
0
0
15
0
0
0
0
0
% N
% Pro:
50
8
8
0
8
0
15
15
22
0
8
8
8
8
8
% P
% Gln:
0
15
22
8
8
0
8
0
8
8
0
29
0
0
8
% Q
% Arg:
0
0
29
0
8
0
0
0
0
0
0
8
0
15
0
% R
% Ser:
8
0
8
0
0
8
0
8
8
8
8
8
15
15
0
% S
% Thr:
0
8
0
8
22
8
15
29
0
0
8
0
0
8
0
% T
% Val:
0
8
8
8
0
29
8
0
15
0
15
8
0
0
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _