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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG8
All Species:
1.21
Human Site:
T386
Identified Species:
2.05
UniProt:
Q96MW5
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MW5
NP_115758.3
612
68424
T386
F
Q
K
A
I
Q
E
T
V
E
K
F
Q
E
E
Chimpanzee
Pan troglodytes
XP_511064
394
44531
R218
Y
F
G
L
S
F
S
R
V
G
A
D
F
R
G
Rhesus Macaque
Macaca mulatta
XP_001100394
487
54500
A311
L
L
D
F
P
P
L
A
C
F
L
N
N
I
L
Dog
Lupus familis
XP_546857
624
69140
A388
F
Q
K
A
I
Q
E
A
V
E
K
F
Q
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJA2
640
71600
A392
F
Q
K
A
V
E
E
A
V
E
K
F
Q
D
E
Rat
Rattus norvegicus
NP_001099652
634
70744
A392
F
Q
K
A
V
E
E
A
V
E
K
F
Q
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510195
500
55836
S323
F
L
N
N
I
L
L
S
F
N
D
L
R
L
C
Chicken
Gallus gallus
XP_001232975
677
74631
L376
E
E
M
N
S
Y
T
L
I
S
A
P
A
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013524
634
71570
A368
F
R
K
A
I
Q
E
A
V
D
K
F
Q
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKH0
570
64891
V377
F
E
S
S
V
E
Q
V
D
E
Q
F
E
R
E
Honey Bee
Apis mellifera
XP_623492
605
69076
K376
E
S
F
T
L
I
N
K
I
Q
K
T
N
V
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001204069
378
43256
E202
R
R
M
D
L
F
T
E
A
E
L
R
I
K
F
Poplar Tree
Populus trichocarpa
XP_002308543
575
64166
E388
F
P
S
Y
S
I
G
E
E
Q
Q
E
D
V
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568256
569
63034
E388
F
P
S
S
G
I
N
E
D
S
K
D
D
V
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.7
76.9
86.5
N.A.
86
87.6
N.A.
65.3
63.2
N.A.
67
N.A.
41.5
40.6
N.A.
41.1
Protein Similarity:
100
64.2
77.7
90.3
N.A.
89
91
N.A.
70.7
71.7
N.A.
78.7
N.A.
59.1
62
N.A.
51.1
P-Site Identity:
100
6.6
0
86.6
N.A.
73.3
73.3
N.A.
13.3
0
N.A.
73.3
N.A.
26.6
6.6
N.A.
6.6
P-Site Similarity:
100
13.3
0
93.3
N.A.
93.3
93.3
N.A.
26.6
13.3
N.A.
93.3
N.A.
73.3
33.3
N.A.
26.6
Percent
Protein Identity:
32.3
N.A.
N.A.
32
N.A.
N.A.
Protein Similarity:
49.6
N.A.
N.A.
49.6
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
36
0
0
0
36
8
0
15
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% C
% Asp:
0
0
8
8
0
0
0
0
15
8
8
15
15
22
8
% D
% Glu:
15
15
0
0
0
22
36
22
8
43
0
8
8
15
36
% E
% Phe:
65
8
8
8
0
15
0
0
8
8
0
43
8
0
8
% F
% Gly:
0
0
8
0
8
0
8
0
0
8
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
29
22
0
0
15
0
0
0
8
8
0
% I
% Lys:
0
0
36
0
0
0
0
8
0
0
50
0
0
8
8
% K
% Leu:
8
15
0
8
15
8
15
8
0
0
15
8
0
8
15
% L
% Met:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
15
0
0
15
0
0
8
0
8
15
0
0
% N
% Pro:
0
15
0
0
8
8
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
29
0
0
0
22
8
0
0
15
15
0
36
0
0
% Q
% Arg:
8
15
0
0
0
0
0
8
0
0
0
8
8
15
0
% R
% Ser:
0
8
22
15
22
0
8
8
0
15
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
15
8
0
0
0
8
0
0
15
% T
% Val:
0
0
0
0
22
0
0
8
43
0
0
0
0
29
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _