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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG8
All Species:
13.33
Human Site:
T239
Identified Species:
22.56
UniProt:
Q96MW5
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MW5
NP_115758.3
612
68424
T239
L
R
R
M
D
V
F
T
E
A
E
L
R
V
K
Chimpanzee
Pan troglodytes
XP_511064
394
44531
N79
L
I
Q
Q
L
R
T
N
I
Q
L
P
A
C
L
Rhesus Macaque
Macaca mulatta
XP_001100394
487
54500
D172
R
A
I
F
S
D
E
D
P
L
L
P
P
A
V
Dog
Lupus familis
XP_546857
624
69140
T241
L
R
C
M
D
I
F
T
E
A
E
L
R
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJA2
640
71600
T245
L
R
R
M
D
V
F
T
E
A
E
L
R
V
K
Rat
Rattus norvegicus
NP_001099652
634
70744
T245
L
R
R
M
D
V
F
T
E
A
E
L
R
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510195
500
55836
G184
P
L
A
P
P
A
A
G
Q
R
P
V
N
E
R
Chicken
Gallus gallus
XP_001232975
677
74631
W233
F
L
Q
A
R
D
A
W
L
R
S
I
Q
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013524
634
71570
E226
M
D
V
F
T
E
A
E
L
R
V
K
F
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKH0
570
64891
G226
L
R
R
M
Q
A
F
G
D
N
E
L
R
L
K
Honey Bee
Apis mellifera
XP_623492
605
69076
A231
L
R
I
K
F
L
Q
A
R
D
S
W
L
Q
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001204069
378
43256
V63
A
D
C
S
R
E
I
V
E
D
F
A
V
V
E
Poplar Tree
Populus trichocarpa
XP_002308543
575
64166
E239
A
W
L
T
G
I
L
E
D
L
D
Q
R
N
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568256
569
63034
E239
A
W
L
T
G
I
L
E
D
L
D
Q
K
N
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.7
76.9
86.5
N.A.
86
87.6
N.A.
65.3
63.2
N.A.
67
N.A.
41.5
40.6
N.A.
41.1
Protein Similarity:
100
64.2
77.7
90.3
N.A.
89
91
N.A.
70.7
71.7
N.A.
78.7
N.A.
59.1
62
N.A.
51.1
P-Site Identity:
100
6.6
0
86.6
N.A.
100
100
N.A.
0
0
N.A.
0
N.A.
60
13.3
N.A.
13.3
P-Site Similarity:
100
13.3
0
93.3
N.A.
100
100
N.A.
20
20
N.A.
20
N.A.
73.3
20
N.A.
20
Percent
Protein Identity:
32.3
N.A.
N.A.
32
N.A.
N.A.
Protein Similarity:
49.6
N.A.
N.A.
49.6
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
8
8
8
0
15
22
8
0
29
0
8
8
15
15
% A
% Cys:
0
0
15
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
15
0
0
29
15
0
8
22
15
15
0
0
0
0
% D
% Glu:
0
0
0
0
0
15
8
22
36
0
36
0
0
8
8
% E
% Phe:
8
0
0
15
8
0
36
0
0
0
8
0
8
0
0
% F
% Gly:
0
0
0
0
15
0
0
15
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
15
0
0
22
8
0
8
0
0
8
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
8
8
0
36
% K
% Leu:
50
15
15
0
8
8
15
0
15
22
15
36
8
15
8
% L
% Met:
8
0
0
36
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
8
0
0
8
15
0
% N
% Pro:
8
0
0
8
8
0
0
0
8
0
8
15
8
0
0
% P
% Gln:
0
0
15
8
8
0
8
0
8
8
0
15
8
8
8
% Q
% Arg:
8
43
29
0
15
8
0
0
8
22
0
0
43
0
8
% R
% Ser:
0
0
0
8
8
0
0
0
0
0
15
0
0
0
15
% S
% Thr:
0
0
0
15
8
0
8
29
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
22
0
8
0
0
8
8
8
36
8
% V
% Trp:
0
15
0
0
0
0
0
8
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _