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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG8
All Species:
19.39
Human Site:
S210
Identified Species:
32.82
UniProt:
Q96MW5
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MW5
NP_115758.3
612
68424
S210
Q
S
M
Q
L
M
L
S
Q
L
I
Q
Q
L
R
Chimpanzee
Pan troglodytes
XP_511064
394
44531
S50
R
L
E
R
K
Y
S
S
I
P
V
I
Q
G
I
Rhesus Macaque
Macaca mulatta
XP_001100394
487
54500
Y143
A
I
P
N
D
D
P
Y
F
H
I
T
K
T
I
Dog
Lupus familis
XP_546857
624
69140
S212
Q
S
M
Q
L
M
L
S
Q
L
I
Q
Q
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJA2
640
71600
S216
Q
S
M
Q
L
M
L
S
Q
L
I
Q
Q
L
R
Rat
Rattus norvegicus
NP_001099652
634
70744
S216
Q
S
M
Q
L
M
L
S
Q
L
I
Q
Q
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510195
500
55836
E155
F
H
I
T
K
T
I
E
A
C
R
V
H
L
F
Chicken
Gallus gallus
XP_001232975
677
74631
C204
T
N
I
P
L
P
T
C
L
R
V
I
G
Y
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013524
634
71570
L197
Q
L
M
L
N
Q
L
L
Q
Q
L
R
S
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKH0
570
64891
V197
A
L
W
H
N
M
L
V
Q
L
V
A
Q
L
R
Honey Bee
Apis mellifera
XP_623492
605
69076
P202
G
S
L
R
G
D
L
P
L
A
R
C
L
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001204069
378
43256
R34
P
E
R
L
S
D
E
R
S
Q
V
L
Q
Q
T
Poplar Tree
Populus trichocarpa
XP_002308543
575
64166
Y210
E
C
L
R
I
I
G
Y
L
R
R
I
G
V
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568256
569
63034
Y210
E
C
L
R
I
I
G
Y
L
R
R
I
G
V
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.7
76.9
86.5
N.A.
86
87.6
N.A.
65.3
63.2
N.A.
67
N.A.
41.5
40.6
N.A.
41.1
Protein Similarity:
100
64.2
77.7
90.3
N.A.
89
91
N.A.
70.7
71.7
N.A.
78.7
N.A.
59.1
62
N.A.
51.1
P-Site Identity:
100
13.3
6.6
100
N.A.
100
100
N.A.
6.6
6.6
N.A.
26.6
N.A.
46.6
13.3
N.A.
6.6
P-Site Similarity:
100
33.3
13.3
100
N.A.
100
100
N.A.
20
26.6
N.A.
40
N.A.
53.3
26.6
N.A.
13.3
Percent
Protein Identity:
32.3
N.A.
N.A.
32
N.A.
N.A.
Protein Similarity:
49.6
N.A.
N.A.
49.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% A
% Cys:
0
15
0
0
0
0
0
8
0
8
0
8
0
0
0
% C
% Asp:
0
0
0
0
8
22
0
0
0
0
0
0
0
0
0
% D
% Glu:
15
8
8
0
0
0
8
8
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
22
% F
% Gly:
8
0
0
0
8
0
15
0
0
0
0
0
22
8
0
% G
% His:
0
8
0
8
0
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
8
15
0
15
15
8
0
8
0
36
29
0
0
15
% I
% Lys:
0
0
0
0
15
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
22
22
15
36
0
50
8
29
36
8
8
8
43
15
% L
% Met:
0
0
36
0
0
36
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
15
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
8
0
8
8
0
8
8
8
0
8
0
0
0
0
0
% P
% Gln:
36
0
0
29
0
8
0
0
43
15
0
29
50
15
0
% Q
% Arg:
8
0
8
29
0
0
0
8
0
22
29
8
0
0
36
% R
% Ser:
0
36
0
0
8
0
8
36
8
0
0
0
8
0
8
% S
% Thr:
8
0
0
8
0
8
8
0
0
0
0
8
0
8
8
% T
% Val:
0
0
0
0
0
0
0
8
0
0
29
8
0
15
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
22
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _