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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG8
All Species:
14.55
Human Site:
S169
Identified Species:
24.62
UniProt:
Q96MW5
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MW5
NP_115758.3
612
68424
S169
M
D
T
C
V
R
N
S
Y
Y
E
E
A
L
E
Chimpanzee
Pan troglodytes
XP_511064
394
44531
H9
N
S
L
T
L
N
R
H
T
E
I
L
E
I
L
Rhesus Macaque
Macaca mulatta
XP_001100394
487
54500
R102
I
Q
L
P
A
C
L
R
V
I
G
Y
L
R
R
Dog
Lupus familis
XP_546857
624
69140
S171
M
D
T
C
V
R
N
S
Y
Y
E
E
A
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJA2
640
71600
S175
M
D
T
C
V
R
N
S
Y
H
E
E
A
L
E
Rat
Rattus norvegicus
NP_001099652
634
70744
S175
M
D
T
C
V
R
N
S
Y
Y
E
E
A
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510195
500
55836
M114
V
I
G
Y
L
R
R
M
D
V
F
T
E
A
E
Chicken
Gallus gallus
XP_001232975
677
74631
L163
L
A
A
Y
V
R
R
L
E
K
K
Y
S
S
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013524
634
71570
E156
C
V
R
N
G
Y
Y
E
E
A
L
E
L
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKH0
570
64891
G156
M
E
R
C
I
R
E
G
R
Y
E
E
A
L
E
Honey Bee
Apis mellifera
XP_623492
605
69076
Y161
E
A
L
E
L
S
Q
Y
A
R
Q
L
G
T
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001204069
378
43256
Poplar Tree
Populus trichocarpa
XP_002308543
575
64166
K169
K
L
S
T
M
H
P
K
L
P
V
I
Q
A
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568256
569
63034
K169
K
L
A
T
L
H
P
K
L
P
V
I
Q
A
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.7
76.9
86.5
N.A.
86
87.6
N.A.
65.3
63.2
N.A.
67
N.A.
41.5
40.6
N.A.
41.1
Protein Similarity:
100
64.2
77.7
90.3
N.A.
89
91
N.A.
70.7
71.7
N.A.
78.7
N.A.
59.1
62
N.A.
51.1
P-Site Identity:
100
0
0
100
N.A.
93.3
100
N.A.
13.3
13.3
N.A.
6.6
N.A.
60
0
N.A.
0
P-Site Similarity:
100
13.3
6.6
100
N.A.
100
100
N.A.
26.6
33.3
N.A.
6.6
N.A.
73.3
20
N.A.
0
Percent
Protein Identity:
32.3
N.A.
N.A.
32
N.A.
N.A.
Protein Similarity:
49.6
N.A.
N.A.
49.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
15
0
8
0
0
0
8
8
0
0
36
29
8
% A
% Cys:
8
0
0
36
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
29
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
8
8
0
8
0
0
8
8
15
8
36
43
15
0
43
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
8
0
8
0
0
8
0
0
8
0
8
0
0
% G
% His:
0
0
0
0
0
15
0
8
0
8
0
0
0
0
0
% H
% Ile:
8
8
0
0
8
0
0
0
0
8
8
15
0
8
8
% I
% Lys:
15
0
0
0
0
0
0
15
0
8
8
0
0
0
8
% K
% Leu:
8
15
22
0
29
0
8
8
15
0
8
15
15
36
22
% L
% Met:
36
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
8
29
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
15
0
0
15
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
8
0
15
0
0
% Q
% Arg:
0
0
15
0
0
50
22
8
8
8
0
0
0
8
8
% R
% Ser:
0
8
8
0
0
8
0
29
0
0
0
0
8
8
0
% S
% Thr:
0
0
29
22
0
0
0
0
8
0
0
8
0
8
0
% T
% Val:
8
8
0
0
36
0
0
0
8
8
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
0
8
8
8
29
29
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _