Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EP400 All Species: 20.3
Human Site: Y2284 Identified Species: 44.67
UniProt: Q96L91 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96L91 NP_056224.2 3160 343617 Y2284 E A K L P P V Y V R K E R K R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105546 3128 340368 Y2249 E A K L P P V Y V R K E R K R
Dog Lupus familis XP_543352 3119 338624 Y2269 E S K L P P V Y V R K E R R R
Cat Felis silvestris
Mouse Mus musculus Q8CHI8 3072 337131 Q2260 K N L L L K Q Q T P F A K P L
Rat Rattus norvegicus NP_001100619 3034 333215 Q2225 K N L L L K Q Q T P F A K P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510861 3116 343098 Y2247 E S K L P P V Y V R K E R K R
Chicken Gallus gallus XP_001234820 3075 339704 Y2243 E S K L P P V Y V R K E R K R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663240 1764 194643 S1025 V L I D S L L S M D Q Y R G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NDJ2 3198 350220 P2356 Q P A P P P L P Q Q Q Q P Q Q
Honey Bee Apis mellifera XP_396786 2758 308573 A2019 H K E E S V Y A P R S L F D R
Nematode Worm Caenorhab. elegans Q9NEL2 2395 268708 T1656 P T T T A T T T T T V P Q Q Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.5 82.9 N.A. 84.4 83.5 N.A. 74.4 70.1 N.A. 33 N.A. 28.6 26.9 22.1 N.A.
Protein Similarity: 100 N.A. 97.3 88 N.A. 88.8 87.9 N.A. 81.9 79.3 N.A. 40.7 N.A. 45.3 44.1 37.5 N.A.
P-Site Identity: 100 N.A. 100 86.6 N.A. 6.6 6.6 N.A. 93.3 93.3 N.A. 6.6 N.A. 13.3 13.3 0 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 20 20 N.A. 100 100 N.A. 26.6 N.A. 60 20 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 10 0 10 0 0 10 0 0 0 19 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 10 0 0 0 10 0 % D
% Glu: 46 0 10 10 0 0 0 0 0 0 0 46 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 19 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 19 10 46 0 0 19 0 0 0 0 46 0 19 37 0 % K
% Leu: 0 10 19 64 19 10 19 0 0 0 0 10 0 0 19 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 10 0 10 55 55 0 10 10 19 0 10 10 19 0 % P
% Gln: 10 0 0 0 0 0 19 19 10 10 19 10 10 19 19 % Q
% Arg: 0 0 0 0 0 0 0 0 0 55 0 0 55 10 55 % R
% Ser: 0 28 0 0 19 0 0 10 0 0 10 0 0 0 0 % S
% Thr: 0 10 10 10 0 10 10 10 28 10 0 0 0 0 0 % T
% Val: 10 0 0 0 0 10 46 0 46 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 46 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _