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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EP400 All Species: 11.52
Human Site: T1206 Identified Species: 25.33
UniProt: Q96L91 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96L91 NP_056224.2 3160 343617 T1206 T Q F F R G L T A F T R V R W
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105546 3128 340368 T1171 T Q F F R G F T A F T R V R W
Dog Lupus familis XP_543352 3119 338624 A1208 K Q F F R G Y A S F M R V R W
Cat Felis silvestris
Mouse Mus musculus Q8CHI8 3072 337131 T1205 K Q F F R G Y T A F S R V H W
Rat Rattus norvegicus NP_001100619 3034 333215 T1168 K Q F F R G Y T A F S R V H W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510861 3116 343098 Q1166 K Q F F K G H Q A F T K V R W
Chicken Gallus gallus XP_001234820 3075 339704 P1168 K Q L F K G H P A F M K M R W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663240 1764 194643
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NDJ2 3198 350220 R1294 G K Y R F H I R V R S A E L A
Honey Bee Apis mellifera XP_396786 2758 308573 R992 I Q D H Q S F R R K K W K Y L
Nematode Worm Caenorhab. elegans Q9NEL2 2395 268708 W629 W E M E F K K W C P A L K I L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.5 82.9 N.A. 84.4 83.5 N.A. 74.4 70.1 N.A. 33 N.A. 28.6 26.9 22.1 N.A.
Protein Similarity: 100 N.A. 97.3 88 N.A. 88.8 87.9 N.A. 81.9 79.3 N.A. 40.7 N.A. 45.3 44.1 37.5 N.A.
P-Site Identity: 100 N.A. 93.3 66.6 N.A. 73.3 73.3 N.A. 66.6 46.6 N.A. 0 N.A. 0 6.6 0 N.A.
P-Site Similarity: 100 N.A. 93.3 73.3 N.A. 80 80 N.A. 80 66.6 N.A. 0 N.A. 26.6 13.3 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 55 0 10 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 10 0 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 0 0 55 64 19 0 19 0 0 64 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 64 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 10 0 10 19 0 0 0 0 0 0 19 0 % H
% Ile: 10 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % I
% Lys: 46 10 0 0 19 10 10 0 0 10 10 19 19 0 0 % K
% Leu: 0 0 10 0 0 0 10 0 0 0 0 10 0 10 19 % L
% Met: 0 0 10 0 0 0 0 0 0 0 19 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % P
% Gln: 0 73 0 0 10 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 46 0 0 19 10 10 0 46 0 46 0 % R
% Ser: 0 0 0 0 0 10 0 0 10 0 28 0 0 0 0 % S
% Thr: 19 0 0 0 0 0 0 37 0 0 28 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 55 0 0 % V
% Trp: 10 0 0 0 0 0 0 10 0 0 0 10 0 0 64 % W
% Tyr: 0 0 10 0 0 0 28 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _