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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC2
All Species:
23.33
Human Site:
S416
Identified Species:
42.78
UniProt:
Q96KP1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KP1
NP_060773.3
924
104066
S416
L
D
N
D
T
R
P
S
V
L
G
H
L
S
Q
Chimpanzee
Pan troglodytes
XP_518202
924
104044
S416
L
D
N
D
T
R
P
S
V
L
G
H
L
S
Q
Rhesus Macaque
Macaca mulatta
XP_001089411
924
104086
S416
L
D
N
D
T
R
P
S
M
L
G
H
L
S
Q
Dog
Lupus familis
XP_535863
924
103977
V416
L
D
T
D
A
R
P
V
V
L
G
H
L
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4H1
924
103941
S416
L
D
N
D
V
R
P
S
V
L
G
H
L
S
Q
Rat
Rattus norvegicus
O54921
924
104013
S416
L
D
N
D
A
R
P
S
V
L
G
H
L
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507793
924
104426
S416
M
D
G
D
S
R
P
S
P
L
S
H
L
S
Q
Chicken
Gallus gallus
NP_001006376
194
21265
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956898
918
103337
S409
G
L
D
L
D
R
S
S
V
L
N
R
I
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQQ9
894
100711
A405
H
T
S
K
D
S
G
A
Q
E
K
A
K
N
R
Honey Bee
Apis mellifera
XP_001122322
875
98525
K390
V
Q
S
N
K
Q
S
K
S
D
K
N
D
G
M
Nematode Worm
Caenorhab. elegans
Q22706
884
100396
A397
Q
T
Q
F
L
E
K
A
K
L
E
D
L
E
N
Sea Urchin
Strong. purpuratus
XP_001201201
659
72952
K174
E
A
D
E
M
E
L
K
G
E
G
D
G
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.8
95.5
N.A.
93.6
94
N.A.
91.8
20
N.A.
76.7
N.A.
33.2
36.6
26.2
24.6
Protein Similarity:
100
99.8
99.3
97.6
N.A.
96.7
96.8
N.A.
95.6
20.5
N.A.
86.8
N.A.
53.1
57.1
48.4
41.2
P-Site Identity:
100
100
93.3
80
N.A.
93.3
93.3
N.A.
66.6
0
N.A.
33.3
N.A.
0
0
13.3
20
P-Site Similarity:
100
100
100
80
N.A.
93.3
93.3
N.A.
80
0
N.A.
46.6
N.A.
26.6
33.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
16
0
0
16
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
54
16
54
16
0
0
0
0
8
0
16
8
0
0
% D
% Glu:
8
0
0
8
0
16
0
0
0
16
8
0
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
0
8
0
8
0
54
0
8
8
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
54
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
8
8
0
8
16
8
0
16
0
8
0
0
% K
% Leu:
47
8
0
8
8
0
8
0
0
70
0
0
62
0
8
% L
% Met:
8
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% M
% Asn:
0
0
39
8
0
0
0
0
0
0
8
8
0
8
8
% N
% Pro:
0
0
0
0
0
0
54
0
8
0
0
0
0
0
0
% P
% Gln:
8
8
8
0
0
8
0
0
8
0
0
0
0
0
62
% Q
% Arg:
0
0
0
0
0
62
0
0
0
0
0
8
0
0
8
% R
% Ser:
0
0
16
0
8
8
16
54
8
0
8
0
0
70
0
% S
% Thr:
0
16
8
0
24
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
8
0
0
8
47
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _