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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC2
All Species:
25.15
Human Site:
S404
Identified Species:
46.11
UniProt:
Q96KP1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KP1
NP_060773.3
924
104066
S404
K
G
N
P
G
L
H
S
P
M
L
D
L
D
N
Chimpanzee
Pan troglodytes
XP_518202
924
104044
S404
K
G
N
P
G
L
H
S
P
M
L
D
L
D
N
Rhesus Macaque
Macaca mulatta
XP_001089411
924
104086
S404
K
A
N
P
G
L
H
S
P
M
L
D
L
D
N
Dog
Lupus familis
XP_535863
924
103977
S404
K
G
T
P
G
L
H
S
P
M
L
D
L
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4H1
924
103941
S404
K
G
H
P
G
P
H
S
P
M
L
D
L
D
N
Rat
Rattus norvegicus
O54921
924
104013
S404
K
G
N
P
G
P
H
S
P
M
L
D
L
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507793
924
104426
S404
K
G
N
P
V
L
H
S
T
L
L
D
M
D
G
Chicken
Gallus gallus
NP_001006376
194
21265
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956898
918
103337
K397
E
D
F
I
K
E
Q
K
V
G
G
V
G
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQQ9
894
100711
Q393
Y
L
E
W
T
F
R
Q
T
F
D
Q
H
T
S
Honey Bee
Apis mellifera
XP_001122322
875
98525
N378
N
S
N
G
E
N
L
N
K
I
K
L
V
Q
S
Nematode Worm
Caenorhab. elegans
Q22706
884
100396
S385
Y
Y
V
W
L
E
K
S
L
W
D
M
Q
T
Q
Sea Urchin
Strong. purpuratus
XP_001201201
659
72952
G162
E
S
N
E
V
D
G
G
D
E
G
K
E
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.8
95.5
N.A.
93.6
94
N.A.
91.8
20
N.A.
76.7
N.A.
33.2
36.6
26.2
24.6
Protein Similarity:
100
99.8
99.3
97.6
N.A.
96.7
96.8
N.A.
95.6
20.5
N.A.
86.8
N.A.
53.1
57.1
48.4
41.2
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
93.3
N.A.
66.6
0
N.A.
0
N.A.
0
6.6
6.6
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
93.3
93.3
N.A.
80
0
N.A.
13.3
N.A.
6.6
33.3
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
8
0
0
8
0
16
54
0
54
16
% D
% Glu:
16
0
8
8
8
16
0
0
0
8
0
0
8
0
0
% E
% Phe:
0
0
8
0
0
8
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
47
0
8
47
0
8
8
0
8
16
0
8
0
8
% G
% His:
0
0
8
0
0
0
54
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
54
0
0
0
8
0
8
8
8
0
8
8
0
0
0
% K
% Leu:
0
8
0
0
8
39
8
0
8
8
54
8
47
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
47
0
8
8
0
0
% M
% Asn:
8
0
54
0
0
8
0
8
0
0
0
0
0
0
39
% N
% Pro:
0
0
0
54
0
16
0
0
47
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
8
0
0
0
8
8
8
8
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
16
0
0
0
0
0
62
0
0
0
0
0
0
16
% S
% Thr:
0
0
8
0
8
0
0
0
16
0
0
0
0
16
8
% T
% Val:
0
0
8
0
16
0
0
0
8
0
0
8
8
0
0
% V
% Trp:
0
0
0
16
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
16
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _