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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG3
All Species:
26.06
Human Site:
S596
Identified Species:
47.78
UniProt:
Q96JB2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JB2
NP_113619.1
828
94096
S596
I
Q
S
L
L
G
A
S
E
S
I
S
K
N
K
Chimpanzee
Pan troglodytes
XP_001158886
790
89707
Y569
L
V
C
L
S
K
L
Y
R
C
I
D
R
A
V
Rhesus Macaque
Macaca mulatta
XP_001096875
828
94056
S596
I
Q
S
L
L
G
A
S
E
S
I
S
K
N
K
Dog
Lupus familis
XP_848489
830
94828
S598
I
Q
S
L
L
G
A
S
E
S
I
S
K
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI04
820
93264
S588
I
Q
S
L
L
G
A
S
E
S
I
S
K
N
K
Rat
Rattus norvegicus
NP_001012157
828
94228
S596
I
Q
S
L
L
G
A
S
E
S
I
S
K
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417041
835
94848
A593
V
H
S
L
L
G
A
A
D
A
I
S
K
N
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137512
820
93798
S589
I
Q
S
L
L
H
A
S
D
I
I
Q
K
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q961G1
905
101221
A584
I
Q
S
V
S
H
A
A
G
K
I
S
A
N
K
Honey Bee
Apis mellifera
XP_393867
799
92557
K562
V
Q
S
I
E
N
A
K
Q
E
I
E
K
R
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196648
781
87158
C568
I
H
S
L
N
V
A
C
Q
G
I
T
K
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177485
784
88591
T558
L
I
I
K
R
S
T
T
M
D
G
Q
L
F
L
Baker's Yeast
Sacchar. cerevisiae
P40094
801
92526
Y573
I
V
S
L
R
N
A
Y
D
M
V
I
K
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
98.9
95
N.A.
94.9
96.2
N.A.
N.A.
86.4
N.A.
77
N.A.
40.2
41.5
N.A.
47.5
Protein Similarity:
100
95.4
99.7
97.1
N.A.
96.9
98.1
N.A.
N.A.
92.5
N.A.
87
N.A.
56.4
60.5
N.A.
63.1
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
66.6
N.A.
73.3
N.A.
53.3
33.3
N.A.
46.6
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
80
N.A.
66.6
53.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.7
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.8
43
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
85
16
0
8
0
0
8
8
8
% A
% Cys:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
24
8
0
8
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
39
8
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
47
0
0
8
8
8
0
0
0
0
% G
% His:
0
16
0
0
0
16
0
0
0
0
0
0
0
0
0
% H
% Ile:
70
8
8
8
0
0
0
0
0
8
85
8
0
0
0
% I
% Lys:
0
0
0
8
0
8
0
8
0
8
0
0
77
0
70
% K
% Leu:
16
0
0
77
54
0
8
0
0
0
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
16
0
0
0
0
0
0
0
62
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
62
0
0
0
0
0
0
16
0
0
16
0
0
0
% Q
% Arg:
0
0
0
0
16
0
0
0
8
0
0
0
8
16
0
% R
% Ser:
0
0
85
0
16
8
0
47
0
39
0
54
0
8
8
% S
% Thr:
0
0
0
0
0
0
8
8
0
0
0
8
0
0
0
% T
% Val:
16
16
0
8
0
8
0
0
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _