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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
22.12
Human Site:
Y550
Identified Species:
32.44
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
Y550
K
E
G
S
S
F
A
Y
I
S
W
K
F
E
C
Chimpanzee
Pan troglodytes
XP_516333
835
93255
Y731
K
E
G
S
S
F
A
Y
I
S
W
K
F
E
C
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
Y550
K
E
G
S
S
F
A
Y
I
S
W
K
F
E
C
Dog
Lupus familis
XP_534241
2041
231068
V1577
W
S
L
T
K
E
K
V
E
E
L
I
K
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
Y547
K
E
G
S
S
F
A
Y
I
S
W
K
F
E
C
Rat
Rattus norvegicus
Q5XI55
651
74658
Y547
K
E
G
S
S
F
A
Y
I
S
W
K
F
E
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
H543
K
E
G
S
S
S
A
H
V
S
W
K
F
E
C
Chicken
Gallus gallus
Q5ZJM3
651
73884
S547
K
E
G
S
S
S
A
S
I
S
W
K
F
E
C
Frog
Xenopus laevis
NP_001116357
635
72527
A532
T
E
G
S
S
S
A
A
I
S
W
K
I
E
C
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
R540
T
E
G
A
S
F
G
R
M
S
W
K
F
N
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
M529
K
V
E
R
D
W
K
M
A
Y
L
A
R
L
E
Honey Bee
Apis mellifera
XP_392561
589
68873
G487
G
T
N
E
I
E
G
G
M
F
R
K
V
E
H
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
F504
P
G
N
I
S
W
H
F
D
L
K
S
L
K
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
D600
G
I
A
T
A
A
F
D
G
I
Q
E
S
K
W
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
F261
K
M
S
Y
C
I
A
F
G
K
D
G
V
V
D
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
F280
C
P
E
G
V
L
K
F
I
M
E
E
I
T
N
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
80
86.6
73.3
60
N.A.
6.6
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
93.3
86.6
73.3
73.3
N.A.
13.3
20
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
7
7
57
7
7
0
0
7
0
0
0
% A
% Cys:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
57
% C
% Asp:
0
0
0
0
7
0
0
7
7
0
7
0
0
0
7
% D
% Glu:
0
57
13
7
0
13
0
0
7
7
7
13
0
57
7
% E
% Phe:
0
0
0
0
0
38
7
19
0
7
0
0
50
0
0
% F
% Gly:
13
7
57
7
0
0
13
7
13
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
7
% H
% Ile:
0
7
0
7
7
7
0
0
50
7
0
7
13
0
0
% I
% Lys:
57
0
0
0
7
0
19
0
0
7
7
63
7
13
7
% K
% Leu:
0
0
7
0
0
7
0
0
0
7
13
0
7
7
0
% L
% Met:
0
7
0
0
0
0
0
7
13
7
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
0
0
0
0
0
0
0
7
7
% N
% Pro:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% Q
% Arg:
0
0
0
7
0
0
0
7
0
0
7
0
7
0
7
% R
% Ser:
0
7
7
50
63
19
0
7
0
57
0
7
7
0
0
% S
% Thr:
13
7
0
13
0
0
0
0
0
0
0
0
0
7
0
% T
% Val:
0
7
0
0
7
0
0
7
7
0
0
0
13
7
0
% V
% Trp:
7
0
0
0
0
13
0
0
0
0
57
0
0
0
7
% W
% Tyr:
0
0
0
7
0
0
0
32
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _