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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
33.64
Human Site:
Y539
Identified Species:
49.33
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
Y539
E
T
D
W
H
M
V
Y
L
A
R
K
E
G
S
Chimpanzee
Pan troglodytes
XP_516333
835
93255
Y720
E
T
D
W
H
M
V
Y
L
A
R
K
E
G
S
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
Y539
E
T
D
W
H
M
V
Y
L
A
R
K
E
G
S
Dog
Lupus familis
XP_534241
2041
231068
N1566
P
D
F
N
Y
I
L
N
M
S
L
W
S
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
Y536
E
K
D
W
N
M
V
Y
L
A
R
K
E
G
S
Rat
Rattus norvegicus
Q5XI55
651
74658
Y536
E
K
D
W
N
M
V
Y
L
A
R
K
E
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
Y532
E
R
D
W
N
M
V
Y
L
A
R
K
E
G
S
Chicken
Gallus gallus
Q5ZJM3
651
73884
Y536
E
T
D
W
K
M
V
Y
L
A
R
K
E
G
S
Frog
Xenopus laevis
NP_001116357
635
72527
Y521
E
S
D
W
K
M
V
Y
L
A
R
T
E
G
S
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
Y529
E
H
D
W
Q
M
V
Y
L
A
R
T
E
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
N518
K
A
Q
F
S
S
K
N
I
F
R
K
V
E
R
Honey Bee
Apis mellifera
XP_392561
589
68873
G476
K
I
L
T
N
I
S
G
W
E
N
G
T
N
E
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
R493
M
T
Y
L
C
R
K
R
G
D
A
P
G
N
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
E589
S
V
L
A
S
G
E
E
L
P
S
G
I
A
T
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
N250
Q
P
Y
I
Y
S
I
N
W
N
K
K
M
S
Y
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
P269
G
S
P
D
A
L
L
P
R
T
R
C
P
E
G
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
100
100
0
N.A.
86.6
86.6
N.A.
86.6
93.3
80
73.3
N.A.
13.3
0
6.6
N.A.
P-Site Similarity:
100
100
100
40
N.A.
93.3
93.3
N.A.
93.3
93.3
86.6
80
N.A.
33.3
20
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
7
0
0
0
0
57
7
0
0
7
7
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
7
57
7
0
0
0
0
0
7
0
0
0
0
0
% D
% Glu:
57
0
0
0
0
0
7
7
0
7
0
0
57
13
7
% E
% Phe:
0
0
7
7
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
7
0
7
7
0
0
13
7
57
7
% G
% His:
0
7
0
0
19
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
7
0
13
7
0
7
0
0
0
7
0
7
% I
% Lys:
13
13
0
0
13
0
13
0
0
0
7
57
0
0
0
% K
% Leu:
0
0
13
7
0
7
13
0
63
0
7
0
0
7
0
% L
% Met:
7
0
0
0
0
57
0
0
7
0
0
0
7
0
0
% M
% Asn:
0
0
0
7
25
0
0
19
0
7
7
0
0
13
0
% N
% Pro:
7
7
7
0
0
0
0
7
0
7
0
7
7
0
0
% P
% Gln:
7
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
0
0
7
0
7
7
0
69
0
0
0
7
% R
% Ser:
7
13
0
0
13
13
7
0
0
7
7
0
7
7
50
% S
% Thr:
0
32
0
7
0
0
0
0
0
7
0
13
7
0
13
% T
% Val:
0
7
0
0
0
0
57
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
57
0
0
0
0
13
0
0
7
0
0
0
% W
% Tyr:
0
0
13
0
13
0
0
57
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _