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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
36.97
Human Site:
Y504
Identified Species:
54.22
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
Y504
Y
N
I
V
K
D
R
Y
V
R
V
S
N
N
N
Chimpanzee
Pan troglodytes
XP_516333
835
93255
Y685
Y
N
I
V
K
D
R
Y
V
R
V
S
N
N
N
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
Y504
Y
N
I
V
K
D
R
Y
V
R
V
S
N
N
N
Dog
Lupus familis
XP_534241
2041
231068
E1531
D
P
V
K
A
W
K
E
A
Q
E
K
A
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
Y501
Y
D
I
V
R
D
R
Y
I
R
V
S
D
N
N
Rat
Rattus norvegicus
Q5XI55
651
74658
Y501
Y
D
I
V
R
D
R
Y
I
R
V
S
D
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
Y497
Y
N
A
V
K
D
S
Y
T
R
I
S
N
N
N
Chicken
Gallus gallus
Q5ZJM3
651
73884
Y501
Y
N
V
V
E
D
S
Y
T
R
I
S
N
N
N
Frog
Xenopus laevis
NP_001116357
635
72527
Y486
Y
N
V
V
E
D
T
Y
T
R
T
S
N
N
N
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
Y494
Y
N
V
T
K
D
C
Y
Y
R
V
S
N
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
Y483
K
R
Q
L
N
V
R
Y
S
C
A
T
D
T
Y
Honey Bee
Apis mellifera
XP_392561
589
68873
L441
T
G
S
Y
E
W
R
L
A
R
G
E
I
S
E
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
Y458
Y
D
V
I
T
D
T
Y
S
Q
P
P
E
I
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
V554
L
D
A
L
R
E
L
V
A
D
L
S
K
Y
Q
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
R215
D
V
R
Y
V
W
N
R
E
D
H
V
W
C
E
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
Y234
A
W
D
M
P
H
M
Y
Y
K
N
W
G
K
K
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
100
100
0
N.A.
73.3
73.3
N.A.
73.3
66.6
66.6
60
N.A.
13.3
13.3
20
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
80
86.6
80
66.6
N.A.
33.3
26.6
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
40
0
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
13
0
7
0
0
0
19
0
7
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
7
0
0
0
7
0
% C
% Asp:
13
25
7
0
0
63
0
0
0
13
0
0
19
0
0
% D
% Glu:
0
0
0
0
19
7
0
7
7
0
7
7
7
0
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
7
0
7
7
7
% G
% His:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
32
7
0
0
0
0
13
0
13
0
7
7
0
% I
% Lys:
7
0
0
7
32
0
7
0
0
7
0
7
7
7
7
% K
% Leu:
7
0
0
13
0
0
7
7
0
0
7
0
0
0
0
% L
% Met:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
44
0
0
7
0
7
0
0
0
7
0
44
50
50
% N
% Pro:
0
7
0
0
7
0
0
0
0
0
7
7
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
13
0
0
0
0
13
% Q
% Arg:
0
7
7
0
19
0
44
7
0
63
0
0
0
0
0
% R
% Ser:
0
0
7
0
0
0
13
0
13
0
0
63
0
7
0
% S
% Thr:
7
0
0
7
7
0
13
0
19
0
7
7
0
7
0
% T
% Val:
0
7
32
50
7
7
0
7
19
0
38
7
0
0
0
% V
% Trp:
0
7
0
0
0
19
0
0
0
0
0
7
7
0
0
% W
% Tyr:
63
0
0
13
0
0
0
75
13
0
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _