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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
28.18
Human Site:
Y282
Identified Species:
41.33
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
Y282
A
K
E
V
E
D
H
Y
C
D
A
C
Q
F
S
Chimpanzee
Pan troglodytes
XP_516333
835
93255
D467
D
R
S
L
L
P
S
D
D
E
L
K
W
G
A
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
Y282
A
K
K
V
E
D
H
Y
C
D
A
C
Q
F
S
Dog
Lupus familis
XP_534241
2041
231068
Y336
A
N
R
V
E
D
H
Y
C
D
V
C
Q
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
Y279
A
K
N
V
E
N
H
Y
C
D
A
C
Q
L
S
Rat
Rattus norvegicus
Q5XI55
651
74658
Y279
A
K
N
V
E
D
H
Y
C
D
A
C
Q
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
Y275
A
N
V
V
E
D
H
Y
C
N
L
C
Q
F
S
Chicken
Gallus gallus
Q5ZJM3
651
73884
Y278
A
D
R
V
E
N
H
Y
C
S
Q
C
Q
F
C
Frog
Xenopus laevis
NP_001116357
635
72527
Y263
A
N
R
V
E
N
H
Y
C
E
K
C
K
H
S
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
F267
A
G
R
V
E
N
H
F
C
H
T
C
Q
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
V269
E
G
D
I
R
V
E
V
T
V
C
C
G
Q
E
Honey Bee
Apis mellifera
XP_392561
589
68873
K231
T
A
C
F
S
E
C
K
Q
Q
E
V
M
L
S
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
T248
A
K
L
L
Q
T
R
T
G
R
C
G
E
W
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
V326
I
A
I
S
K
D
G
V
C
D
V
T
K
R
Y
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
E24
L
S
Q
P
V
V
P
E
P
P
A
Q
D
D
K
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
0
93.3
80
N.A.
80
86.6
N.A.
73.3
60
53.3
53.3
N.A.
6.6
6.6
13.3
N.A.
P-Site Similarity:
100
26.6
100
80
N.A.
86.6
86.6
N.A.
80
66.6
73.3
66.6
N.A.
20
13.3
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
20
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
0
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
63
13
0
0
0
0
0
0
0
0
32
0
0
0
13
% A
% Cys:
0
0
7
0
0
0
7
0
63
0
13
63
0
0
7
% C
% Asp:
7
7
7
0
0
38
0
7
7
38
0
0
7
7
0
% D
% Glu:
7
0
7
0
57
7
7
7
0
13
7
0
7
0
7
% E
% Phe:
0
0
0
7
0
0
0
7
0
0
0
0
0
32
0
% F
% Gly:
0
13
0
0
0
0
7
0
7
0
0
7
7
7
0
% G
% His:
0
0
0
0
0
0
57
0
0
7
0
0
0
7
0
% H
% Ile:
7
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
32
7
0
7
0
0
7
0
0
7
7
13
0
7
% K
% Leu:
7
0
7
13
7
0
0
0
0
0
13
0
0
25
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
19
13
0
0
25
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
7
0
7
7
0
7
7
0
0
0
0
0
% P
% Gln:
0
0
7
0
7
0
0
0
7
7
7
7
50
7
0
% Q
% Arg:
0
7
25
0
7
0
7
0
0
7
0
0
0
7
0
% R
% Ser:
0
7
7
7
7
0
7
0
0
7
0
0
0
0
57
% S
% Thr:
7
0
0
0
0
7
0
7
7
0
7
7
0
0
0
% T
% Val:
0
0
7
57
7
13
0
13
0
7
13
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _