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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
23.03
Human Site:
Y185
Identified Species:
33.78
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
Y185
N
I
Q
H
V
L
V
Y
E
N
P
A
L
Q
E
Chimpanzee
Pan troglodytes
XP_516333
835
93255
Y384
N
I
Q
H
V
L
V
Y
E
N
P
A
L
Q
E
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
Y185
N
I
Q
H
V
L
V
Y
E
N
P
A
L
Q
E
Dog
Lupus familis
XP_534241
2041
231068
V238
S
N
I
Q
H
V
L
V
Y
E
N
L
A
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
Y182
N
I
Q
H
V
Q
L
Y
E
N
P
V
L
Q
E
Rat
Rattus norvegicus
Q5XI55
651
74658
Y182
N
I
Q
H
V
Q
L
Y
E
N
P
V
L
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
Y179
N
F
Q
H
V
L
V
Y
E
N
L
S
L
Q
K
Chicken
Gallus gallus
Q5ZJM3
651
73884
T184
L
I
L
A
Y
E
S
T
S
L
Q
Q
K
A
L
Frog
Xenopus laevis
NP_001116357
635
72527
L177
P
E
I
Q
Q
R
A
L
Q
E
I
P
V
S
D
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
Q178
Y
E
D
P
E
L
Q
Q
K
A
L
E
C
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
T187
L
L
L
A
T
G
R
T
L
I
P
V
E
E
L
Honey Bee
Apis mellifera
XP_392561
589
68873
K153
N
L
Q
E
K
A
K
K
V
I
P
I
V
D
L
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
I170
G
P
R
D
E
K
A
I
L
K
D
L
L
H
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
T226
R
V
E
I
Y
R
C
T
M
C
P
T
T
T
R
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
100
100
0
N.A.
80
80
N.A.
73.3
6.6
0
6.6
N.A.
6.6
20
6.6
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
86.6
86.6
N.A.
86.6
6.6
20
13.3
N.A.
20
33.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
7
13
0
0
7
0
19
7
7
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
7
0
0
7
0
0
% C
% Asp:
0
0
7
7
0
0
0
0
0
0
7
0
0
7
7
% D
% Glu:
0
13
7
7
13
7
0
0
38
13
0
7
7
7
32
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
38
7
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
38
13
7
0
0
0
7
0
13
7
7
0
7
0
% I
% Lys:
0
0
0
0
7
7
7
7
7
7
0
0
7
0
7
% K
% Leu:
13
13
13
0
0
32
19
7
13
7
13
13
44
7
19
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
44
7
0
0
0
0
0
0
0
38
7
0
0
0
0
% N
% Pro:
7
7
0
7
0
0
0
0
0
0
50
7
0
0
7
% P
% Gln:
0
0
44
13
7
13
7
7
7
0
7
7
0
38
7
% Q
% Arg:
7
0
7
0
0
13
7
0
0
0
0
0
0
0
7
% R
% Ser:
7
0
0
0
0
0
7
0
7
0
0
7
0
7
0
% S
% Thr:
0
0
0
0
7
0
0
19
0
0
0
7
7
7
0
% T
% Val:
0
7
0
0
38
7
25
7
7
0
0
19
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
7
0
0
0
13
0
0
38
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _