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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
16.36
Human Site:
T595
Identified Species:
24
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
T595
D
T
A
Q
V
E
L
T
G
D
N
S
L
H
S
Chimpanzee
Pan troglodytes
XP_516333
835
93255
T776
D
T
A
R
V
E
L
T
G
D
N
S
L
H
S
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
T595
D
T
A
R
V
E
L
T
G
D
N
N
L
H
S
Dog
Lupus familis
XP_534241
2041
231068
R1622
D
K
V
E
A
Q
E
R
E
D
I
L
A
G
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
L592
E
T
A
Q
V
N
L
L
G
D
K
N
L
R
S
Rat
Rattus norvegicus
Q5XI55
651
74658
L592
E
M
A
Q
V
N
L
L
G
D
R
N
L
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
T588
D
K
A
Q
V
E
L
T
G
D
K
N
L
R
S
Chicken
Gallus gallus
Q5ZJM3
651
73884
V592
P
T
A
E
V
I
L
V
G
D
N
S
L
S
S
Frog
Xenopus laevis
NP_001116357
635
72527
N577
P
E
A
E
V
E
V
N
S
D
T
N
F
H
S
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
P585
N
E
T
T
T
E
F
P
G
D
G
E
L
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
S574
T
F
G
D
G
K
I
S
V
T
V
D
A
T
D
Honey Bee
Apis mellifera
XP_392561
589
68873
A532
V
R
I
F
H
L
Q
A
I
S
K
V
F
H
D
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
S549
M
R
L
P
I
D
C
S
A
L
T
I
E
D
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
D645
A
N
D
A
P
E
R
D
P
K
D
W
I
L
E
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
D306
R
L
R
Y
S
L
N
D
D
E
I
Y
Q
L
A
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
S325
W
S
A
T
L
E
Q
S
R
R
L
K
A
A
A
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
93.3
86.6
13.3
N.A.
60
53.3
N.A.
73.3
66.6
40
40
N.A.
0
6.6
0
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
73.3
66.6
N.A.
80
73.3
60
46.6
N.A.
20
6.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
57
7
7
0
0
7
7
0
0
0
19
7
13
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
32
0
7
7
0
7
0
13
7
63
7
7
0
7
13
% D
% Glu:
13
13
0
19
0
50
7
0
7
7
0
7
7
0
7
% E
% Phe:
0
7
0
7
0
0
7
0
0
0
0
0
13
0
0
% F
% Gly:
0
0
7
0
7
0
0
0
50
0
7
0
0
7
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
38
0
% H
% Ile:
0
0
7
0
7
7
7
0
7
0
13
7
7
0
0
% I
% Lys:
0
13
0
0
0
7
0
0
0
7
19
7
0
0
0
% K
% Leu:
0
7
7
0
7
13
44
13
0
7
7
7
50
13
0
% L
% Met:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
7
7
0
0
0
13
7
7
0
0
25
32
0
0
0
% N
% Pro:
13
0
0
7
7
0
0
7
7
0
0
0
0
0
7
% P
% Gln:
0
0
0
25
0
7
13
0
0
0
0
0
7
0
0
% Q
% Arg:
7
13
7
13
0
0
7
7
7
7
7
0
0
19
0
% R
% Ser:
0
7
0
0
7
0
0
19
7
7
0
19
0
7
57
% S
% Thr:
7
32
7
13
7
0
0
25
0
7
13
0
0
7
0
% T
% Val:
7
0
7
0
50
0
7
7
7
0
7
7
0
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _