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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
14.55
Human Site:
T132
Identified Species:
21.33
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
T132
S
Q
Q
P
A
A
S
T
Q
L
P
T
T
P
S
Chimpanzee
Pan troglodytes
XP_516333
835
93255
T331
S
Q
Q
P
A
A
S
T
Q
L
P
T
T
P
S
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
T132
S
Q
Q
P
A
A
S
T
Q
L
P
T
T
P
S
Dog
Lupus familis
XP_534241
2041
231068
T185
S
Q
Q
P
A
S
S
T
Q
L
P
I
T
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
A129
F
S
Q
H
P
A
A
A
K
L
P
L
E
Q
S
Rat
Rattus norvegicus
Q5XI55
651
74658
V129
F
S
Q
H
P
A
A
V
R
L
P
A
E
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
L126
T
S
P
N
Q
P
I
L
S
W
P
A
E
P
A
Chicken
Gallus gallus
Q5ZJM3
651
73884
Q131
S
E
T
V
A
I
T
Q
A
I
A
H
Q
P
S
Frog
Xenopus laevis
NP_001116357
635
72527
R124
S
T
P
P
A
F
S
R
T
P
V
P
N
P
V
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
P125
P
P
V
P
A
P
P
P
S
L
S
S
T
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
S134
P
P
Q
Q
S
T
T
S
T
T
P
L
F
I
K
Honey Bee
Apis mellifera
XP_392561
589
68873
N100
L
Q
K
L
L
N
K
N
S
L
S
K
I
P
I
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
A117
T
P
A
N
P
N
A
A
S
D
S
E
K
R
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
F173
K
E
E
R
D
Y
A
F
L
L
Q
L
L
F
W
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
100
100
80
N.A.
33.3
26.6
N.A.
13.3
26.6
33.3
33.3
N.A.
13.3
20
0
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
46.6
40
N.A.
26.6
46.6
33.3
40
N.A.
33.3
26.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
44
32
25
13
7
0
7
13
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% D
% Glu:
0
13
7
0
0
0
0
0
0
0
0
7
19
0
0
% E
% Phe:
13
0
0
0
0
7
0
7
0
0
0
0
7
7
7
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
13
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
7
7
0
0
7
0
7
7
7
7
% I
% Lys:
7
0
7
0
0
0
7
0
7
0
0
7
7
0
7
% K
% Leu:
7
0
0
7
7
0
0
7
7
57
0
19
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
13
0
13
0
7
0
0
0
0
7
0
0
% N
% Pro:
13
19
13
38
19
13
7
7
0
7
50
7
0
44
7
% P
% Gln:
0
32
44
7
7
0
0
7
25
0
7
0
7
19
0
% Q
% Arg:
0
0
0
7
0
0
0
7
7
0
0
0
0
7
0
% R
% Ser:
38
19
0
0
7
7
32
7
25
0
19
7
0
0
44
% S
% Thr:
13
7
7
0
0
7
13
25
13
7
0
19
32
0
0
% T
% Val:
0
0
7
7
0
0
0
7
0
0
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _