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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
30.91
Human Site:
S636
Identified Species:
45.33
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
S636
H
T
Q
L
F
R
Q
S
L
N
D
H
E
E
N
Chimpanzee
Pan troglodytes
XP_516333
835
93255
S817
H
T
Q
L
F
R
Q
S
L
N
D
H
E
E
N
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
S636
H
T
Q
L
F
R
Q
S
L
N
D
H
E
E
N
Dog
Lupus familis
XP_534241
2041
231068
E1663
Y
G
R
R
I
V
P
E
I
T
A
M
K
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
S633
H
T
Q
L
F
R
Q
S
L
N
D
S
G
E
N
Rat
Rattus norvegicus
Q5XI55
651
74658
S633
H
T
Q
L
F
R
Q
S
L
N
D
H
A
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
S629
H
T
Q
L
F
R
Q
S
L
N
D
R
G
E
K
Chicken
Gallus gallus
Q5ZJM3
651
73884
S633
H
T
Q
L
F
R
N
S
L
A
G
C
G
E
N
Frog
Xenopus laevis
NP_001116357
635
72527
T618
H
T
Q
I
F
R
Q
T
L
D
C
K
E
N
S
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
S626
H
A
Q
L
F
R
Q
S
L
K
D
T
E
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
Q615
Q
H
T
Q
L
F
R
Q
S
L
N
S
R
D
Y
Honey Bee
Apis mellifera
XP_392561
589
68873
L573
A
Q
L
F
R
Q
S
L
E
I
E
D
D
Q
S
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
G590
F
R
T
E
L
K
R
G
G
G
A
R
T
E
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
P686
K
S
Y
K
I
T
T
P
G
F
Q
A
N
L
F
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
R347
S
K
S
S
N
R
G
R
E
S
G
S
A
D
W
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
E366
D
I
K
R
P
I
P
E
D
A
P
V
P
D
V
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
100
100
0
N.A.
86.6
93.3
N.A.
80
66.6
53.3
66.6
N.A.
0
0
6.6
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
86.6
93.3
N.A.
80
66.6
80
73.3
N.A.
20
33.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
0
0
0
13
13
7
13
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
7
7
44
7
7
19
7
% D
% Glu:
0
0
0
7
0
0
0
13
13
0
7
0
32
50
0
% E
% Phe:
7
0
0
7
57
7
0
0
0
7
0
0
0
0
7
% F
% Gly:
0
7
0
0
0
0
7
7
13
7
13
0
19
0
0
% G
% His:
57
7
0
0
0
0
0
0
0
0
0
25
0
0
0
% H
% Ile:
0
7
0
7
13
7
0
0
7
7
0
0
0
0
0
% I
% Lys:
7
7
7
7
0
7
0
0
0
7
0
7
7
7
7
% K
% Leu:
0
0
7
50
13
0
0
7
57
7
0
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
7
0
7
0
0
38
7
0
7
7
38
% N
% Pro:
0
0
0
0
7
0
13
7
0
0
7
0
7
0
0
% P
% Gln:
7
7
57
7
0
7
50
7
0
0
7
0
0
7
0
% Q
% Arg:
0
7
7
13
7
63
13
7
0
0
0
13
7
0
0
% R
% Ser:
7
7
7
7
0
0
7
50
7
7
0
19
0
0
19
% S
% Thr:
0
50
13
0
0
7
7
7
0
7
0
7
7
0
0
% T
% Val:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _