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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
37.58
Human Site:
S446
Identified Species:
55.11
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
S446
V
E
L
V
E
F
I
S
P
K
T
P
K
P
G
Chimpanzee
Pan troglodytes
XP_516333
835
93255
S627
V
E
L
V
E
F
I
S
P
K
T
P
K
P
G
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
S446
V
E
L
V
E
F
I
S
P
K
T
P
K
P
G
Dog
Lupus familis
XP_534241
2041
231068
F1173
R
K
V
L
F
T
C
F
K
R
N
D
K
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
S443
V
E
L
V
E
F
I
S
P
K
T
P
R
P
G
Rat
Rattus norvegicus
Q5XI55
651
74658
S443
V
E
L
V
E
F
I
S
P
K
T
P
R
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
S439
V
E
L
V
E
F
I
S
P
K
T
P
K
P
G
Chicken
Gallus gallus
Q5ZJM3
651
73884
S442
V
E
L
A
E
F
I
S
P
K
T
P
K
P
G
Frog
Xenopus laevis
NP_001116357
635
72527
S427
V
E
L
V
E
F
M
S
P
K
T
T
K
P
G
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
S431
V
E
L
V
E
F
I
S
P
K
S
P
Q
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
M425
L
F
L
S
Q
R
N
M
Y
E
V
I
G
L
T
Honey Bee
Apis mellifera
XP_392561
589
68873
L385
L
L
Q
F
I
E
S
L
N
K
Y
R
Q
S
T
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
G402
K
I
G
W
E
K
I
G
D
D
L
G
G
R
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
S498
T
L
D
S
D
N
S
S
S
F
P
E
Q
F
L
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
T159
E
S
K
F
N
C
G
T
V
E
I
Y
K
C
N
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
A178
L
R
V
K
R
G
R
A
G
D
F
A
N
V
F
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
100
93.3
86.6
86.6
N.A.
6.6
6.6
13.3
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
100
93.3
93.3
100
N.A.
26.6
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
7
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
7
7
0
0
0
0
0
0
7
0
% C
% Asp:
0
0
7
0
7
0
0
0
7
13
0
7
0
0
0
% D
% Glu:
7
57
0
0
63
7
0
0
0
13
0
7
0
0
7
% E
% Phe:
0
7
0
13
7
57
0
7
0
7
7
0
0
7
7
% F
% Gly:
0
0
7
0
0
7
7
7
7
0
0
7
13
0
57
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
0
57
0
0
0
7
7
0
0
7
% I
% Lys:
7
7
7
7
0
7
0
0
7
63
0
0
50
0
0
% K
% Leu:
19
13
63
7
0
0
0
7
0
0
7
0
0
7
7
% L
% Met:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
7
7
0
7
0
7
0
7
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
57
0
7
50
0
57
0
% P
% Gln:
0
0
7
0
7
0
0
0
0
0
0
0
19
0
0
% Q
% Arg:
7
7
0
0
7
7
7
0
0
7
0
7
13
13
0
% R
% Ser:
0
7
0
13
0
0
13
63
7
0
7
0
0
7
0
% S
% Thr:
7
0
0
0
0
7
0
7
0
0
50
7
0
0
13
% T
% Val:
57
0
13
50
0
0
0
0
7
0
7
0
0
7
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _