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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
21.21
Human Site:
S426
Identified Species:
31.11
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
S426
K
Q
R
Q
L
F
L
S
E
N
R
R
K
E
L
Chimpanzee
Pan troglodytes
XP_516333
835
93255
S607
K
Q
R
Q
L
F
L
S
E
N
R
R
K
E
L
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
S426
K
Q
R
Q
L
F
L
S
E
N
R
R
K
E
L
Dog
Lupus familis
XP_534241
2041
231068
V567
N
G
K
G
I
P
V
V
E
H
K
V
E
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
S423
K
Q
R
Q
L
S
L
S
E
S
R
R
K
E
L
Rat
Rattus norvegicus
Q5XI55
651
74658
S423
K
Q
R
Q
L
L
L
S
E
S
R
R
K
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
P419
T
Q
R
Q
L
S
L
P
Q
S
R
K
Q
E
L
Chicken
Gallus gallus
Q5ZJM3
651
73884
S422
K
K
K
Q
Q
S
L
S
E
G
R
R
K
E
L
Frog
Xenopus laevis
NP_001116357
635
72527
P407
K
M
R
Q
Q
S
V
P
E
H
R
K
Q
E
L
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
G411
A
E
R
Q
Q
F
L
G
A
E
R
K
Q
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
R409
D
A
I
R
A
K
R
R
Q
N
C
T
A
D
R
Honey Bee
Apis mellifera
XP_392561
589
68873
R370
Q
Q
T
V
M
N
R
R
N
I
C
S
E
N
K
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
M387
V
C
E
L
M
E
M
M
A
Q
E
A
K
N
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
L475
L
K
M
I
K
Q
V
L
V
D
L
K
N
A
P
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
G144
S
E
N
M
T
P
L
G
S
Q
G
P
N
G
E
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
R163
G
A
Y
E
R
F
P
R
Y
T
E
A
W
Q
L
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
86.6
86.6
N.A.
53.3
66.6
46.6
40
N.A.
6.6
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
60
N.A.
93.3
93.3
N.A.
80
80
73.3
66.6
N.A.
26.6
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
13
0
0
7
0
0
0
13
0
0
13
7
7
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
13
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% D
% Glu:
0
13
7
7
0
7
0
0
50
7
13
0
13
50
7
% E
% Phe:
0
0
0
0
0
32
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
0
7
0
0
0
13
0
7
7
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
7
% H
% Ile:
0
0
7
7
7
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
44
13
13
0
7
7
0
0
0
0
7
25
44
7
7
% K
% Leu:
7
0
0
7
38
7
57
7
0
0
7
0
0
0
63
% L
% Met:
0
7
7
7
13
0
7
7
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
0
7
0
0
7
25
0
0
13
13
0
% N
% Pro:
0
0
0
0
0
13
7
13
0
0
0
7
0
0
7
% P
% Gln:
7
44
0
57
19
7
0
0
13
13
0
0
19
13
0
% Q
% Arg:
0
0
50
7
7
0
13
19
0
0
57
38
0
0
7
% R
% Ser:
7
0
0
0
0
25
0
38
7
19
0
7
0
0
0
% S
% Thr:
7
0
7
0
7
0
0
0
0
7
0
7
0
0
0
% T
% Val:
7
0
0
7
0
0
19
7
7
0
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _