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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
10.3
Human Site:
S267
Identified Species:
15.11
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
S267
R
D
R
S
L
L
P
S
D
D
E
L
K
W
G
Chimpanzee
Pan troglodytes
XP_516333
835
93255
C452
N
N
V
L
C
S
K
C
G
G
Q
T
R
S
R
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
N267
R
D
R
S
L
L
P
N
D
D
E
L
K
W
G
Dog
Lupus familis
XP_534241
2041
231068
N321
R
G
E
S
L
F
P
N
D
D
E
M
K
W
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
N264
R
D
E
A
L
L
P
N
D
D
E
L
K
W
G
Rat
Rattus norvegicus
Q5XI55
651
74658
N264
R
D
E
A
L
P
P
N
D
D
E
L
K
W
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
F260
S
R
N
K
L
S
P
F
D
N
E
R
R
W
G
Chicken
Gallus gallus
Q5ZJM3
651
73884
T263
K
R
D
Y
L
S
P
T
D
D
D
L
R
W
N
Frog
Xenopus laevis
NP_001116357
635
72527
S248
A
R
D
A
L
S
P
S
D
E
D
L
R
W
G
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
S252
P
S
G
S
L
S
P
S
S
D
D
L
H
W
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
S254
R
V
C
G
S
E
E
S
R
L
R
R
T
E
R
Honey Bee
Apis mellifera
XP_392561
589
68873
T216
W
F
K
Y
K
F
F
T
W
V
D
S
P
K
C
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
R233
D
G
C
N
T
E
M
R
F
P
R
Y
N
N
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
W311
P
M
L
Y
E
K
G
W
N
K
K
L
N
Y
V
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
D9
S
N
R
D
Q
K
F
D
L
H
V
I
P
D
L
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
0
93.3
66.6
N.A.
80
73.3
N.A.
40
40
46.6
46.6
N.A.
13.3
0
0
N.A.
P-Site Similarity:
100
20
100
80
N.A.
93.3
86.6
N.A.
53.3
66.6
73.3
53.3
N.A.
13.3
20
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
13
0
7
0
0
7
0
0
0
0
0
0
7
% C
% Asp:
7
25
13
7
0
0
0
7
50
44
25
0
0
7
7
% D
% Glu:
0
0
19
0
7
13
7
0
0
7
38
0
0
7
0
% E
% Phe:
0
7
0
0
0
13
13
7
7
0
0
0
0
0
0
% F
% Gly:
0
13
7
7
0
0
7
0
7
7
0
0
0
0
44
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
7
0
7
7
7
13
7
0
0
7
7
0
32
7
0
% K
% Leu:
0
0
7
7
57
19
0
0
7
7
0
50
0
0
7
% L
% Met:
0
7
0
0
0
0
7
0
0
0
0
7
0
0
0
% M
% Asn:
7
13
7
7
0
0
0
25
7
7
0
0
13
7
7
% N
% Pro:
13
0
0
0
0
7
57
0
0
7
0
0
13
0
7
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
38
19
19
0
0
0
0
7
7
0
13
13
25
0
13
% R
% Ser:
13
7
0
25
7
32
0
25
7
0
0
7
0
7
0
% S
% Thr:
0
0
0
0
7
0
0
13
0
0
0
7
7
0
0
% T
% Val:
0
7
7
0
0
0
0
0
0
7
7
0
0
0
7
% V
% Trp:
7
0
0
0
0
0
0
7
7
0
0
0
0
57
0
% W
% Tyr:
0
0
0
19
0
0
0
0
0
0
0
7
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _