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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NGLY1
All Species:
11.82
Human Site:
S212
Identified Species:
17.33
UniProt:
Q96IV0
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IV0
NP_001138765.1
654
74390
S212
R
K
S
Q
E
K
L
S
R
A
R
K
L
D
K
Chimpanzee
Pan troglodytes
XP_516333
835
93255
K409
L
K
R
K
S
Q
E
K
L
S
R
A
R
K
L
Rhesus Macaque
Macaca mulatta
XP_001093251
654
74564
S212
R
K
S
Q
E
K
L
S
R
V
R
K
L
D
K
Dog
Lupus familis
XP_534241
2041
231068
S266
R
R
S
Q
E
K
L
S
R
A
R
K
L
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI78
651
74257
F209
R
K
A
Q
E
K
L
F
R
A
R
K
L
D
K
Rat
Rattus norvegicus
Q5XI55
651
74658
F209
R
K
S
Q
E
K
L
F
R
A
R
K
L
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507250
647
73725
A206
M
K
C
R
E
N
L
A
R
A
S
Q
A
D
A
Chicken
Gallus gallus
Q5ZJM3
651
73884
A208
E
K
A
Q
R
K
L
A
Q
A
T
R
L
D
K
Frog
Xenopus laevis
NP_001116357
635
72527
T203
A
K
S
L
D
S
D
T
S
V
N
L
E
D
F
Zebra Danio
Brachydanio rerio
Q503I8
644
72470
K198
S
R
A
K
E
R
L
K
Q
A
N
D
A
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRR5
631
73298
A210
I
D
I
Q
D
Q
I
A
S
G
E
R
Q
E
K
Honey Bee
Apis mellifera
XP_392561
589
68873
R173
T
R
I
R
Q
L
H
R
H
I
K
V
N
Q
T
Nematode Worm
Caenorhab. elegans
Q9TW67
606
69129
T190
F
T
W
F
D
R
P
T
C
P
K
C
T
L
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGY9
721
82428
A255
K
G
R
C
G
E
W
A
N
C
F
T
L
Y
C
Baker's Yeast
Sacchar. cerevisiae
Q02890
363
42466
Red Bread Mold
Neurospora crassa
Q7SI01
382
43903
Conservation
Percent
Protein Identity:
100
72.8
96.9
22.5
N.A.
84.5
84.4
N.A.
70.6
68.8
64.2
57.1
N.A.
32.8
35.1
31.3
N.A.
Protein Similarity:
100
74.2
98.9
27.3
N.A.
91.4
90.3
N.A.
81
81.3
78.1
72.6
N.A.
53.2
53
49
N.A.
P-Site Identity:
100
13.3
93.3
93.3
N.A.
86.6
93.3
N.A.
40
53.3
20
26.6
N.A.
13.3
0
6.6
N.A.
P-Site Similarity:
100
33.3
93.3
100
N.A.
93.3
93.3
N.A.
60
80
33.3
60
N.A.
53.3
26.6
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.9
23.2
Protein Similarity:
N.A.
N.A.
N.A.
46.6
37.7
36.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
19
0
0
0
0
25
0
44
0
7
13
0
13
% A
% Cys:
0
0
7
7
0
0
0
0
7
7
0
7
0
0
7
% C
% Asp:
0
7
0
0
19
0
7
0
0
0
0
7
0
57
0
% D
% Glu:
7
0
0
0
44
7
7
0
0
0
7
0
7
7
0
% E
% Phe:
7
0
0
7
0
0
0
13
0
0
7
0
0
0
7
% F
% Gly:
0
7
0
0
7
0
0
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% H
% Ile:
7
0
13
0
0
0
7
0
0
7
0
0
0
0
0
% I
% Lys:
7
50
0
13
0
38
0
13
0
0
13
32
0
7
50
% K
% Leu:
7
0
0
7
0
7
50
0
7
0
0
7
44
7
7
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
7
0
13
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
44
7
13
0
0
13
0
0
7
7
7
0
% Q
% Arg:
32
19
13
13
7
13
0
7
38
0
38
13
7
0
0
% R
% Ser:
7
0
32
0
7
7
0
19
13
7
7
0
0
0
0
% S
% Thr:
7
7
0
0
0
0
0
13
0
0
7
7
7
0
7
% T
% Val:
0
0
0
0
0
0
0
0
0
13
0
7
0
0
0
% V
% Trp:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _