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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GMPPA All Species: 30.3
Human Site: S322 Identified Species: 55.56
UniProt: Q96IJ6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96IJ6 NP_037467.2 420 46291 S322 E G V R L R E S I V L H G A T
Chimpanzee Pan troglodytes XP_516110 207 23228 V112 G S P E A F F V L N A D V C S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851514 420 46076 S322 E G V R L R E S I V L H G A T
Cat Felis silvestris
Mouse Mus musculus Q922H4 420 46226 S322 E G V R L R E S I V L H G A T
Rat Rattus norvegicus Q5XIC1 420 46173 S322 E G V R L R E S I V L H G A T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q66KG5 426 46865 S328 A G V R I R E S I I L H G A V
Zebra Danio Brachydanio rerio Q6GMK8 422 46992 S324 A G V R V R E S I I L H G A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7JZB4 369 40430 G274 P T A K I G E G C R I G P N V
Honey Bee Apis mellifera XP_396879 420 46316 S321 R G V R I R E S I I L A N A H
Nematode Worm Caenorhab. elegans A3QMC8 365 40081 N270 P S A T V G E N C V I G P D V
Sea Urchin Strong. purpuratus XP_782147 422 46752 S323 A G V R V R E S I V L E G A T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P41940 361 39547 T266 P T A K I S S T A K I G P D V
Red Bread Mold Neurospora crassa Q7RVR8 364 40035 N269 P S A K I G K N C R I G P N V
Conservation
Percent
Protein Identity: 100 49 N.A. 95.7 N.A. 97.6 96.6 N.A. N.A. N.A. 72.5 72.9 N.A. 32.1 54.5 30.4 61.6
Protein Similarity: 100 49.2 N.A. 97.6 N.A. 98.8 98 N.A. N.A. N.A. 84.2 86.2 N.A. 49 70.7 48.3 76.5
P-Site Identity: 100 0 N.A. 100 N.A. 100 100 N.A. N.A. N.A. 73.3 80 N.A. 6.6 60 13.3 80
P-Site Similarity: 100 13.3 N.A. 100 N.A. 100 100 N.A. N.A. N.A. 86.6 93.3 N.A. 26.6 73.3 33.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.8 31.6
Protein Similarity: N.A. N.A. N.A. N.A. 51.1 48.3
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 0 31 0 8 0 0 0 8 0 8 8 0 62 0 % A
% Cys: 0 0 0 0 0 0 0 0 24 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 0 16 0 % D
% Glu: 31 0 0 8 0 0 77 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % F
% Gly: 8 62 0 0 0 24 0 8 0 0 0 31 54 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 47 0 0 8 % H
% Ile: 0 0 0 0 39 0 0 0 62 24 31 0 0 0 0 % I
% Lys: 0 0 0 24 0 0 8 0 0 8 0 0 0 0 0 % K
% Leu: 0 0 0 0 31 0 0 0 8 0 62 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 16 0 8 0 0 8 16 0 % N
% Pro: 31 0 8 0 0 0 0 0 0 0 0 0 31 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 62 0 62 0 0 0 16 0 0 0 0 0 % R
% Ser: 0 24 0 0 0 8 8 62 0 0 0 0 0 0 8 % S
% Thr: 0 16 0 8 0 0 0 8 0 0 0 0 0 0 47 % T
% Val: 0 0 62 0 24 0 0 8 0 47 0 0 8 0 39 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _