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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REEP6
All Species:
16.36
Human Site:
S159
Identified Species:
30
UniProt:
Q96HR9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HR9
NP_612402.1
184
20733
S159
D
R
I
M
N
D
L
S
G
R
A
L
D
A
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095757
184
20648
S159
D
R
I
V
N
N
L
S
G
R
A
L
D
A
A
Dog
Lupus familis
XP_855124
414
44146
S155
D
S
V
V
R
D
F
S
G
R
A
L
D
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JM62
201
22185
S159
D
S
A
A
S
Q
L
S
G
R
A
L
D
L
A
Rat
Rattus norvegicus
Q5XI60
211
23295
S159
D
S
A
A
S
Q
L
S
G
R
A
L
D
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507345
189
21424
K160
D
S
V
V
K
D
L
K
D
K
A
K
E
T
A
Chicken
Gallus gallus
XP_001233336
302
33303
K273
D
N
V
V
K
D
L
K
D
K
A
A
E
T
A
Frog
Xenopus laevis
NP_001088158
188
21408
G159
D
S
V
V
S
D
L
G
G
Q
A
L
N
T
A
Zebra Danio
Brachydanio rerio
Q4KMI4
268
30092
E215
D
Q
S
D
S
R
T
E
H
S
D
E
D
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610936
178
20295
F153
N
K
L
V
R
P
Y
F
L
K
H
H
E
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780122
198
22388
T159
E
D
S
L
D
K
V
T
D
I
A
S
S
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12402
180
20251
V156
D
R
Y
I
L
R
D
V
S
K
T
E
K
D
E
Red Bread Mold
Neurospora crassa
Q871R7
168
19003
T144
F
R
S
F
L
A
P
T
L
G
R
Y
F
Q
N
Conservation
Percent
Protein Identity:
100
N.A.
96.1
36.7
N.A.
73.1
69.6
N.A.
57.1
35
56.9
20.5
N.A.
46.2
N.A.
N.A.
50
Protein Similarity:
100
N.A.
98.3
39.6
N.A.
81.5
77.7
N.A.
73.5
45.7
75
30.2
N.A.
66.8
N.A.
N.A.
65.1
P-Site Identity:
100
N.A.
86.6
60
N.A.
60
60
N.A.
33.3
33.3
46.6
26.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
100
73.3
N.A.
66.6
66.6
N.A.
60
60
80
40
N.A.
46.6
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.4
34.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50
50
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
16
0
8
0
0
0
0
70
8
0
24
70
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
77
8
0
8
8
39
8
0
24
0
8
0
47
8
0
% D
% Glu:
8
0
0
0
0
0
0
8
0
0
0
16
24
0
8
% E
% Phe:
8
0
0
8
0
0
8
8
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
47
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
8
8
0
0
0
% H
% Ile:
0
0
16
8
0
0
0
0
0
8
0
0
0
8
0
% I
% Lys:
0
8
0
0
16
8
0
16
0
31
0
8
8
0
0
% K
% Leu:
0
0
8
8
16
0
54
0
16
0
0
47
0
8
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
16
8
0
0
0
0
0
0
8
0
8
% N
% Pro:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
16
0
0
0
8
0
0
0
8
0
% Q
% Arg:
0
31
0
0
16
16
0
0
0
39
8
0
0
0
0
% R
% Ser:
0
39
24
0
31
0
0
39
8
8
0
8
8
8
0
% S
% Thr:
0
0
0
0
0
0
8
16
0
0
8
0
0
31
0
% T
% Val:
0
0
31
47
0
0
8
8
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _