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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SENP5
All Species:
9.7
Human Site:
S228
Identified Species:
23.7
UniProt:
Q96HI0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HI0
NP_689912.2
755
86733
S228
Q
H
R
R
I
K
L
S
P
L
M
M
Y
E
K
Chimpanzee
Pan troglodytes
XP_526436
861
97496
S333
Q
H
R
R
I
K
L
S
P
L
M
M
Y
E
K
Rhesus Macaque
Macaca mulatta
XP_001099537
755
86288
S228
R
H
R
R
I
K
L
S
P
L
M
M
Y
E
K
Dog
Lupus familis
XP_545156
771
88369
V244
N
Q
H
R
R
I
K
V
S
P
F
M
M
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6NXL6
749
86082
V222
Q
L
N
Q
H
R
R
V
R
A
S
L
M
M
Y
Rat
Rattus norvegicus
Q9EQE1
588
67234
S69
N
S
L
Y
N
A
A
S
L
F
G
F
P
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422763
535
61118
I14
M
V
K
F
R
Y
R
I
I
K
S
P
E
L
R
Frog
Xenopus laevis
NP_001131048
722
83319
F196
M
H
K
K
L
S
L
F
T
I
Y
G
R
L
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09353
697
79628
V178
D
V
L
F
E
K
V
V
K
T
P
N
K
Q
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q02724
621
72359
K102
E
T
L
W
N
S
G
K
Y
L
W
H
T
F
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
94.5
88.5
N.A.
81.5
21.9
N.A.
N.A.
45.1
41
N.A.
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
100
86.9
97.2
93
N.A.
88.4
37.7
N.A.
N.A.
55.3
55.5
N.A.
N.A.
N.A.
N.A.
38.6
N.A.
P-Site Identity:
100
100
93.3
13.3
N.A.
6.6
6.6
N.A.
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
20
N.A.
26.6
13.3
N.A.
N.A.
13.3
46.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
10
0
0
0
0
0
0
0
10
30
10
% E
% Phe:
0
0
0
20
0
0
0
10
0
10
10
10
0
20
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
10
10
0
0
0
% G
% His:
0
40
10
0
10
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
30
10
0
10
10
10
0
0
0
0
0
% I
% Lys:
0
0
20
10
0
40
10
10
10
10
0
0
10
0
30
% K
% Leu:
0
10
30
0
10
0
40
0
10
40
0
10
0
20
10
% L
% Met:
20
0
0
0
0
0
0
0
0
0
30
40
20
10
0
% M
% Asn:
20
0
10
0
20
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
30
10
10
10
10
0
0
% P
% Gln:
30
10
0
10
0
0
0
0
0
0
0
0
0
10
20
% Q
% Arg:
10
0
30
40
20
10
20
0
10
0
0
0
10
0
10
% R
% Ser:
0
10
0
0
0
20
0
40
10
0
20
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
10
10
0
0
10
0
0
% T
% Val:
0
20
0
0
0
0
10
30
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
10
0
10
0
0
10
0
10
0
30
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _