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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKB
All Species:
23.03
Human Site:
Y145
Identified Species:
38.97
UniProt:
Q96GD4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96GD4
NP_004208.2
344
39280
Y145
L
R
L
Y
N
Y
F
Y
D
R
R
R
I
Y
L
Chimpanzee
Pan troglodytes
XP_511856
395
44529
Y196
L
R
L
Y
N
Y
F
Y
D
R
R
R
I
Y
L
Rhesus Macaque
Macaca mulatta
XP_001118154
562
62706
Y363
L
R
L
Y
N
Y
F
Y
D
R
R
R
I
Y
L
Dog
Lupus familis
XP_849906
346
39574
Y145
L
R
L
Y
N
Y
F
Y
D
R
R
R
I
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
O70126
345
39306
Y150
L
Q
L
Y
N
Y
F
Y
D
Q
Q
R
I
Y
L
Rat
Rattus norvegicus
O55099
343
39216
Y148
L
Q
L
Y
N
Y
F
Y
D
Q
Q
R
I
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
F127
E
L
Q
K
F
S
K
F
D
E
Q
R
T
A
T
Chicken
Gallus gallus
XP_425725
409
46456
H215
L
R
L
Y
G
Y
F
H
D
V
T
R
V
Y
L
Frog
Xenopus laevis
Q6DE08
361
41717
H161
L
R
M
Y
N
Y
F
H
D
R
K
R
I
Y
L
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
I129
D
D
T
R
V
F
L
I
L
E
Y
A
P
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
E131
S
R
I
Y
L
A
L
E
I
A
S
E
G
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01427
305
34731
Y133
S
E
P
T
A
A
K
Y
M
Y
E
I
A
D
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M077
294
33954
C123
L
Y
K
D
L
Q
K
C
K
Y
F
S
E
R
R
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
H172
T
K
S
Y
G
Y
F
H
D
E
K
R
V
Y
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
60.3
91.3
N.A.
84.9
84.5
N.A.
61.9
56.9
67.5
66.5
N.A.
44.4
N.A.
53.4
N.A.
Protein Similarity:
100
86.3
60.6
95
N.A.
91.5
90.4
N.A.
72
66.5
78.6
76.1
N.A.
62.5
N.A.
65.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
80
80
N.A.
13.3
66.6
80
0
N.A.
20
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
80
100
6.6
N.A.
26.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.9
36.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68
59.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
15
0
0
0
8
0
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
8
0
0
0
0
72
0
0
0
0
8
0
% D
% Glu:
8
8
0
0
0
0
0
8
0
22
8
8
8
8
0
% E
% Phe:
0
0
0
0
8
8
65
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
15
0
0
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
22
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
8
0
0
8
50
0
0
% I
% Lys:
0
8
8
8
0
0
22
0
8
0
15
0
0
0
0
% K
% Leu:
65
8
50
0
15
0
15
0
8
0
0
0
0
0
72
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
15
8
0
0
8
0
0
0
15
22
0
0
0
0
% Q
% Arg:
0
50
0
8
0
0
0
0
0
36
29
72
0
15
8
% R
% Ser:
15
0
8
0
0
8
0
0
0
0
8
8
0
0
0
% S
% Thr:
8
0
8
8
0
0
0
0
0
0
8
0
8
0
8
% T
% Val:
0
0
0
0
8
0
0
0
0
8
0
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
72
0
65
0
50
0
15
8
0
0
65
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _