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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AURKB All Species: 16.97
Human Site: T35 Identified Species: 28.72
UniProt: Q96GD4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96GD4 NP_004208.2 344 39280 T35 V L R K E P V T P S A L V L M
Chimpanzee Pan troglodytes XP_511856 395 44529 T86 V L R K E P V T P S A L V L M
Rhesus Macaque Macaca mulatta XP_001118154 562 62706 T253 V L R K E P V T P S A L V L M
Dog Lupus familis XP_849906 346 39574 T35 V L R K D P A T P S A L V L M
Cat Felis silvestris
Mouse Mus musculus O70126 345 39306 T35 V L R K E P A T T S A L A L V
Rat Rattus norvegicus O55099 343 39216 V35 V L R K E P A V T P A Q A L M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521399 303 34973 G35 S L D D F D I G R P L G K G K
Chicken Gallus gallus XP_425725 409 46456 K105 V P S K N S E K P Q Q A P V P
Frog Xenopus laevis Q6DE08 361 41717 Q51 N L L A Q R T Q L S R I T P S
Zebra Danio Brachydanio rerio Q6NW76 320 36928 G35 P D T H A V S G P G R V P V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKN7 329 38282 H39 M C L K M M S H D A Y G Q P Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O01427 305 34731 G39 I G R P L G K G K F G S V Y L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M077 294 33954 D32 R W T L S D F D I G K P L G R
Baker's Yeast Sacchar. cerevisiae P38991 367 42927 N62 K L N R L P V N N K K F L D M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.8 60.3 91.3 N.A. 84.9 84.5 N.A. 61.9 56.9 67.5 66.5 N.A. 44.4 N.A. 53.4 N.A.
Protein Similarity: 100 86.3 60.6 95 N.A. 91.5 90.4 N.A. 72 66.5 78.6 76.1 N.A. 62.5 N.A. 65.1 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 73.3 60 N.A. 6.6 20 13.3 6.6 N.A. 6.6 N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 80 60 N.A. 13.3 26.6 26.6 20 N.A. 20 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 54.9 36.7 N.A.
Protein Similarity: N.A. N.A. N.A. 68 59.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 22 0 0 8 43 8 15 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 8 8 15 0 8 8 0 0 0 0 8 0 % D
% Glu: 0 0 0 0 36 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 8 0 8 0 0 8 0 8 0 0 0 % F
% Gly: 0 8 0 0 0 8 0 22 0 15 8 15 0 15 0 % G
% His: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 8 0 8 0 0 8 0 0 0 % I
% Lys: 8 0 0 58 0 0 8 8 8 8 15 0 8 0 15 % K
% Leu: 0 65 15 8 15 0 0 0 8 0 8 36 15 43 8 % L
% Met: 8 0 0 0 8 8 0 0 0 0 0 0 0 0 43 % M
% Asn: 8 0 8 0 8 0 0 8 8 0 0 0 0 0 0 % N
% Pro: 8 8 0 8 0 50 0 0 43 15 0 8 15 15 8 % P
% Gln: 0 0 0 0 8 0 0 8 0 8 8 8 8 0 0 % Q
% Arg: 8 0 50 8 0 8 0 0 8 0 15 0 0 0 8 % R
% Ser: 8 0 8 0 8 8 15 0 0 43 0 8 0 0 8 % S
% Thr: 0 0 15 0 0 0 8 36 15 0 0 0 8 0 0 % T
% Val: 50 0 0 0 0 8 29 8 0 0 0 8 36 15 8 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _