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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUS3L
All Species:
34.85
Human Site:
Y604
Identified Species:
54.76
UniProt:
Q96G46
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96G46
NP_001155091.1
650
72594
Y604
R
I
N
E
R
P
P
Y
Y
L
G
R
D
Y
L
Chimpanzee
Pan troglodytes
XP_001146456
627
69991
Y581
R
I
N
E
R
P
P
Y
Y
L
G
R
D
Y
L
Rhesus Macaque
Macaca mulatta
XP_001085581
322
35153
T277
P
T
G
L
G
T
S
T
P
P
S
S
P
V
R
Dog
Lupus familis
XP_542144
645
71422
Y599
R
I
N
E
R
P
P
Y
Y
L
G
R
D
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91XI1
637
71060
Y591
R
I
N
E
R
P
P
Y
Y
L
G
R
D
Y
L
Rat
Rattus norvegicus
Q3KRC5
640
71521
Y594
R
I
N
E
R
P
P
Y
Y
L
G
R
D
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425899
660
74222
Y614
K
I
N
E
R
P
P
Y
Y
I
G
R
D
Y
L
Frog
Xenopus laevis
Q7ZWS1
640
72538
Y594
K
I
N
E
R
P
P
Y
Y
M
G
R
D
Y
L
Zebra Danio
Brachydanio rerio
NP_956968
660
75360
F614
R
I
N
E
R
P
P
F
Y
M
G
R
D
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610000
604
68006
K559
K
I
N
A
R
P
Q
K
Y
R
G
R
D
E
M
Honey Bee
Apis mellifera
XP_393458
618
71672
F572
R
I
N
E
R
P
P
F
Y
K
G
R
D
D
M
Nematode Worm
Caenorhab. elegans
NP_500379
554
62649
R509
R
I
N
D
R
P
P
R
F
C
G
R
N
E
L
Sea Urchin
Strong. purpuratus
XP_793440
655
74135
Y582
K
I
N
E
R
P
P
Y
Y
V
G
R
D
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9T0J6
700
78551
S649
Q
I
N
W
R
P
P
S
Y
F
G
R
D
D
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SG01
737
82594
A685
A
M
N
D
R
P
P
A
Y
K
G
R
N
E
L
Conservation
Percent
Protein Identity:
100
91.3
42.6
86.3
N.A.
82.3
81.6
N.A.
N.A.
63.1
66.3
63.4
N.A.
45.2
43
45.3
52.5
Protein Similarity:
100
92.6
44.9
91.3
N.A.
87.8
87
N.A.
N.A.
75.7
80.7
76.8
N.A.
59.5
63.2
59.5
66.1
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
86.6
86.6
86.6
N.A.
53.3
73.3
60
80
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
66.6
86.6
80
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.4
N.A.
35.1
Protein Similarity:
N.A.
N.A.
N.A.
55
N.A.
50
P-Site Identity:
N.A.
N.A.
N.A.
66.6
N.A.
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
0
14
0
0
0
0
0
0
0
0
80
20
0
% D
% Glu:
0
0
0
67
0
0
0
0
0
0
0
0
0
20
0
% E
% Phe:
0
0
0
0
0
0
0
14
7
7
0
0
0
0
0
% F
% Gly:
0
0
7
0
7
0
0
0
0
0
94
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
87
0
0
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
27
0
0
0
0
0
0
7
0
14
0
0
0
0
0
% K
% Leu:
0
0
0
7
0
0
0
0
0
34
0
0
0
0
80
% L
% Met:
0
7
0
0
0
0
0
0
0
14
0
0
0
0
14
% M
% Asn:
0
0
94
0
0
0
0
0
0
0
0
0
14
0
0
% N
% Pro:
7
0
0
0
0
94
87
0
7
7
0
0
7
0
0
% P
% Gln:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
54
0
0
0
94
0
0
7
0
7
0
94
0
0
7
% R
% Ser:
0
0
0
0
0
0
7
7
0
0
7
7
0
0
0
% S
% Thr:
0
7
0
0
0
7
0
7
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
87
0
0
0
0
54
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _