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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUS3L
All Species:
6.06
Human Site:
T271
Identified Species:
9.52
UniProt:
Q96G46
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96G46
NP_001155091.1
650
72594
T271
Q
V
P
A
G
P
G
T
S
T
P
P
S
S
P
Chimpanzee
Pan troglodytes
XP_001146456
627
69991
T275
Q
V
P
A
G
P
G
T
S
T
P
P
S
S
P
Rhesus Macaque
Macaca mulatta
XP_001085581
322
35153
Dog
Lupus familis
XP_542144
645
71422
A266
Q
A
L
L
E
P
G
A
G
A
L
A
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91XI1
637
71060
A258
Q
L
D
T
V
G
G
A
G
T
P
Q
S
S
P
Rat
Rattus norvegicus
Q3KRC5
640
71521
D261
Q
L
D
N
V
G
G
D
G
A
R
Q
G
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425899
660
74222
T281
L
V
Q
S
P
H
P
T
E
S
E
G
G
C
P
Frog
Xenopus laevis
Q7ZWS1
640
72538
Q261
V
K
E
D
S
A
V
Q
V
T
Q
K
D
S
P
Zebra Danio
Brachydanio rerio
NP_956968
660
75360
R281
N
G
S
D
S
A
N
R
R
E
T
Q
V
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610000
604
68006
Q224
E
I
L
D
A
E
K
Q
T
D
T
K
S
K
P
Honey Bee
Apis mellifera
XP_393458
618
71672
E237
S
I
N
E
T
K
N
E
I
F
K
N
Q
N
T
Nematode Worm
Caenorhab. elegans
NP_500379
554
62649
N216
A
P
L
T
T
V
G
N
L
P
F
R
R
I
C
Sea Urchin
Strong. purpuratus
XP_793440
655
74135
V248
H
N
E
S
P
T
V
V
M
P
T
S
G
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9T0J6
700
78551
E303
Y
D
G
V
K
L
E
E
E
T
K
K
N
G
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SG01
737
82594
A281
D
Q
Y
L
K
W
M
A
K
D
S
E
L
A
R
Conservation
Percent
Protein Identity:
100
91.3
42.6
86.3
N.A.
82.3
81.6
N.A.
N.A.
63.1
66.3
63.4
N.A.
45.2
43
45.3
52.5
Protein Similarity:
100
92.6
44.9
91.3
N.A.
87.8
87
N.A.
N.A.
75.7
80.7
76.8
N.A.
59.5
63.2
59.5
66.1
P-Site Identity:
100
100
0
33.3
N.A.
46.6
26.6
N.A.
N.A.
20
20
6.6
N.A.
13.3
0
6.6
0
P-Site Similarity:
100
100
0
33.3
N.A.
53.3
33.3
N.A.
N.A.
33.3
20
6.6
N.A.
33.3
13.3
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.4
N.A.
35.1
Protein Similarity:
N.A.
N.A.
N.A.
55
N.A.
50
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
14
7
14
0
20
0
14
0
7
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% C
% Asp:
7
7
14
20
0
0
0
7
0
14
0
0
7
7
0
% D
% Glu:
7
0
14
7
7
7
7
14
14
7
7
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% F
% Gly:
0
7
7
0
14
14
40
0
20
0
0
7
20
7
0
% G
% His:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
14
0
0
0
0
0
0
7
0
0
0
0
7
0
% I
% Lys:
0
7
0
0
14
7
7
0
7
0
14
20
0
7
0
% K
% Leu:
7
14
20
14
0
7
0
0
7
0
7
0
7
0
0
% L
% Met:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% M
% Asn:
7
7
7
7
0
0
14
7
0
0
0
7
7
7
0
% N
% Pro:
0
7
14
0
14
20
7
0
0
14
20
14
0
7
54
% P
% Gln:
34
7
7
0
0
0
0
14
0
0
7
20
7
0
0
% Q
% Arg:
0
0
0
0
0
0
0
7
7
0
7
7
7
0
7
% R
% Ser:
7
0
7
14
14
0
0
0
14
7
7
7
34
40
7
% S
% Thr:
0
0
0
14
14
7
0
20
7
34
20
0
0
0
7
% T
% Val:
7
20
0
7
14
7
14
7
7
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _