KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUS3L
All Species:
11.82
Human Site:
S205
Identified Species:
18.57
UniProt:
Q96G46
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96G46
NP_001155091.1
650
72594
S205
A
R
G
T
Q
P
P
S
I
R
N
G
L
D
K
Chimpanzee
Pan troglodytes
XP_001146456
627
69991
S205
A
R
G
T
Q
P
P
S
I
R
N
G
L
D
K
Rhesus Macaque
Macaca mulatta
XP_001085581
322
35153
Dog
Lupus familis
XP_542144
645
71422
P196
E
E
R
V
Q
A
P
P
V
R
N
G
L
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91XI1
637
71060
S194
A
R
C
A
Q
L
P
S
V
R
N
G
L
D
R
Rat
Rattus norvegicus
Q3KRC5
640
71521
S197
A
R
C
A
Q
L
P
S
V
R
N
G
L
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425899
660
74222
L215
K
Q
W
E
G
K
S
L
V
R
N
S
L
S
K
Frog
Xenopus laevis
Q7ZWS1
640
72538
L210
K
E
W
E
G
K
V
L
V
K
N
S
L
D
K
Zebra Danio
Brachydanio rerio
NP_956968
660
75360
Q237
Q
R
E
Q
T
D
E
Q
S
K
N
T
E
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610000
604
68006
E179
Y
D
F
S
R
S
K
E
L
I
K
M
A
E
K
Honey Bee
Apis mellifera
XP_393458
618
71672
K182
Q
I
L
L
R
K
H
K
Y
N
F
Y
K
A
E
Nematode Worm
Caenorhab. elegans
NP_500379
554
62649
K173
E
K
A
L
E
A
I
K
N
E
N
F
E
V
L
Sea Urchin
Strong. purpuratus
XP_793440
655
74135
V191
K
E
T
G
G
K
C
V
V
R
N
L
L
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9T0J6
700
78551
A218
S
L
G
L
L
G
H
A
K
K
S
N
A
A
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SG01
737
82594
V222
E
D
G
R
K
E
L
V
L
T
E
D
P
T
K
Conservation
Percent
Protein Identity:
100
91.3
42.6
86.3
N.A.
82.3
81.6
N.A.
N.A.
63.1
66.3
63.4
N.A.
45.2
43
45.3
52.5
Protein Similarity:
100
92.6
44.9
91.3
N.A.
87.8
87
N.A.
N.A.
75.7
80.7
76.8
N.A.
59.5
63.2
59.5
66.1
P-Site Identity:
100
100
0
46.6
N.A.
66.6
66.6
N.A.
N.A.
26.6
26.6
20
N.A.
6.6
0
6.6
26.6
P-Site Similarity:
100
100
0
60
N.A.
80
80
N.A.
N.A.
40
40
33.3
N.A.
33.3
13.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.4
N.A.
35.1
Protein Similarity:
N.A.
N.A.
N.A.
55
N.A.
50
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
0
7
14
0
14
0
7
0
0
0
0
14
14
0
% A
% Cys:
0
0
14
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
0
0
0
7
0
0
0
0
0
7
0
47
0
% D
% Glu:
20
20
7
14
7
7
7
7
0
7
7
0
14
7
14
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
7
7
0
0
0
% F
% Gly:
0
0
27
7
20
7
0
0
0
0
0
34
0
0
0
% G
% His:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
7
0
14
7
0
0
0
0
0
% I
% Lys:
20
7
0
0
7
27
7
14
7
20
7
0
7
0
47
% K
% Leu:
0
7
7
20
7
14
7
14
14
0
0
7
54
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
7
67
7
0
0
0
% N
% Pro:
0
0
0
0
0
14
34
7
0
0
0
0
7
0
0
% P
% Gln:
14
7
0
7
34
0
0
7
0
0
0
0
0
0
7
% Q
% Arg:
0
34
7
7
14
0
0
0
0
47
0
0
0
0
20
% R
% Ser:
7
0
0
7
0
7
7
27
7
0
7
14
0
14
0
% S
% Thr:
0
0
7
14
7
0
0
0
0
7
0
7
0
7
0
% T
% Val:
0
0
0
7
0
0
7
14
40
0
0
0
0
7
0
% V
% Trp:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _