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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX11
All Species:
19.09
Human Site:
T477
Identified Species:
38.18
UniProt:
Q96FC9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FC9
NP_004390.3
970
108313
T477
Q
T
G
T
E
L
K
T
I
N
D
F
L
F
Q
Chimpanzee
Pan troglodytes
XP_520821
925
103112
T496
Q
T
G
T
E
L
K
T
I
N
D
F
L
F
Q
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
T477
Q
T
G
T
E
L
K
T
I
N
D
F
L
F
Q
Dog
Lupus familis
XP_543872
907
102087
T477
Q
T
G
T
E
L
K
T
I
N
D
F
L
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
S448
Q
T
G
S
E
L
K
S
I
N
D
F
L
F
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
F508
E
L
K
T
I
N
D
F
L
F
Q
S
Q
I
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
T432
M
M
R
T
Y
E
L
T
A
E
G
D
F
F
N
Honey Bee
Apis mellifera
XP_001121183
769
88327
P354
G
A
T
T
K
S
N
P
D
D
F
I
N
V
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
I365
F
E
T
Q
M
D
N
I
N
L
F
K
L
Q
R
Poplar Tree
Populus trichocarpa
XP_002299703
918
103579
A459
N
Y
Q
A
E
E
I
A
A
D
K
K
A
V
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
F429
I
V
T
Y
F
N
K
F
K
S
R
L
N
P
G
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
I582
L
K
A
D
Q
E
G
I
V
L
D
T
S
L
L
Conservation
Percent
Protein Identity:
100
84.4
84.2
73.4
N.A.
68.6
N.A.
N.A.
67.2
N.A.
N.A.
N.A.
N.A.
35.4
34.4
N.A.
42
Protein Similarity:
100
86.4
86.2
80.2
N.A.
76.1
N.A.
N.A.
78.4
N.A.
N.A.
N.A.
N.A.
52.1
52
N.A.
57.9
P-Site Identity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
20
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
20
26.6
N.A.
13.3
Percent
Protein Identity:
31.1
N.A.
N.A.
N.A.
29.2
25.8
Protein Similarity:
51.2
N.A.
N.A.
N.A.
47.3
42.1
P-Site Identity:
6.6
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
9
0
0
0
9
17
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
9
0
9
9
0
9
17
50
9
0
0
9
% D
% Glu:
9
9
0
0
50
25
0
0
0
9
0
0
0
0
0
% E
% Phe:
9
0
0
0
9
0
0
17
0
9
17
42
9
50
0
% F
% Gly:
9
0
42
0
0
0
9
0
0
0
9
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
0
9
17
42
0
0
9
0
9
0
% I
% Lys:
0
9
9
0
9
0
50
0
9
0
9
17
0
0
9
% K
% Leu:
9
9
0
0
0
42
9
0
9
17
0
9
50
9
9
% L
% Met:
9
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
17
17
0
9
42
0
0
17
0
9
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% P
% Gln:
42
0
9
9
9
0
0
0
0
0
9
0
9
9
42
% Q
% Arg:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
9
% R
% Ser:
0
0
0
9
0
9
0
9
0
9
0
9
9
0
0
% S
% Thr:
0
42
25
59
0
0
0
42
0
0
0
9
0
0
0
% T
% Val:
0
9
0
0
0
0
0
0
9
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
9
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _