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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX11 All Species: 21.21
Human Site: S259 Identified Species: 42.42
UniProt: Q96FC9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FC9 NP_004390.3 970 108313 S259 G K D V R L V S L G S R Q N L
Chimpanzee Pan troglodytes XP_520821 925 103112 S278 G K D V R L V S L G S R Q N L
Rhesus Macaque Macaca mulatta XP_001114477 931 104280 S259 G K D V R L V S L G S R Q N L
Dog Lupus familis XP_543872 907 102087 S259 G K D T R L V S L G S R Q N L
Cat Felis silvestris
Mouse Mus musculus Q6AXC6 880 98710 S231 G K E T R L V S L G S R Q T L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517598 930 104705 S276 G K E T R L A S L G S R Q S L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569898 861 96577 G240 V R K L K H V G L M N E R C L
Honey Bee Apis mellifera XP_001121183 769 88327 V180 N Y C I N K N V K K L K H L N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792082 780 88384 H191 Q S L K A C P H F S Q G Q L S
Poplar Tree Populus trichocarpa XP_002299703 918 103579 C241 S N E I N V V C L G S R K N F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22516 861 98787 G244 S R T Y S Q L G Q F T S Q L R
Red Bread Mold Neurospora crassa A7UXD4 1073 119198 P380 K E I V K Q I P L S S R Q K L
Conservation
Percent
Protein Identity: 100 84.4 84.2 73.4 N.A. 68.6 N.A. N.A. 67.2 N.A. N.A. N.A. N.A. 35.4 34.4 N.A. 42
Protein Similarity: 100 86.4 86.2 80.2 N.A. 76.1 N.A. N.A. 78.4 N.A. N.A. N.A. N.A. 52.1 52 N.A. 57.9
P-Site Identity: 100 100 100 93.3 N.A. 80 N.A. N.A. 73.3 N.A. N.A. N.A. N.A. 20 0 N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 N.A. N.A. 86.6 N.A. N.A. N.A. N.A. 53.3 13.3 N.A. 6.6
Percent
Protein Identity: 31.1 N.A. N.A. N.A. 29.2 25.8
Protein Similarity: 51.2 N.A. N.A. N.A. 47.3 42.1
P-Site Identity: 40 N.A. N.A. N.A. 6.6 40
P-Site Similarity: 66.6 N.A. N.A. N.A. 26.6 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 9 0 0 9 0 9 0 0 0 0 0 9 0 % C
% Asp: 0 0 34 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 25 0 0 0 0 0 0 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 9 % F
% Gly: 50 0 0 0 0 0 0 17 0 59 0 9 0 0 0 % G
% His: 0 0 0 0 0 9 0 9 0 0 0 0 9 0 0 % H
% Ile: 0 0 9 17 0 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 9 50 9 9 17 9 0 0 9 9 0 9 9 9 0 % K
% Leu: 0 0 9 9 0 50 9 0 75 0 9 0 0 25 67 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 9 9 0 0 17 0 9 0 0 0 9 0 0 42 9 % N
% Pro: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % P
% Gln: 9 0 0 0 0 17 0 0 9 0 9 0 75 0 0 % Q
% Arg: 0 17 0 0 50 0 0 0 0 0 0 67 9 0 9 % R
% Ser: 17 9 0 0 9 0 0 50 0 17 67 9 0 9 9 % S
% Thr: 0 0 9 25 0 0 0 0 0 0 9 0 0 9 0 % T
% Val: 9 0 0 34 0 9 59 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _