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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYFIP2
All Species:
47.27
Human Site:
Y127
Identified Species:
80
UniProt:
Q96F07
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96F07
NP_001032409.2
1278
148399
Y127
T
K
L
M
K
F
M
Y
F
Q
R
K
A
I
E
Chimpanzee
Pan troglodytes
XP_001137120
1278
148380
Y127
T
K
L
M
K
F
M
Y
F
Q
R
K
A
I
E
Rhesus Macaque
Macaca mulatta
XP_001105005
1359
156392
Y208
T
K
L
M
K
F
M
Y
F
Q
R
K
A
I
E
Dog
Lupus familis
XP_536455
1288
149367
Y137
T
K
L
M
K
F
M
Y
F
Q
R
K
A
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5SQX6
1253
145641
Y127
T
K
L
M
K
F
M
Y
F
Q
R
K
A
I
E
Rat
Rattus norvegicus
NP_001100987
1253
145239
Y127
T
K
L
M
N
F
M
Y
F
Q
R
N
A
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508077
1255
145699
Y127
T
K
L
M
K
F
M
Y
F
Q
R
K
A
I
E
Chicken
Gallus gallus
XP_414567
1253
145683
Y127
T
K
L
M
K
F
M
Y
F
Q
R
K
A
I
E
Frog
Xenopus laevis
Q6GQD1
1253
145619
Y127
T
K
L
M
K
F
M
Y
F
Q
R
K
A
I
E
Zebra Danio
Brachydanio rerio
Q90YM8
1253
145156
Y127
N
K
L
M
N
F
M
Y
F
Q
R
T
A
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VF87
1291
149242
Y127
N
K
L
L
N
F
M
Y
F
Q
R
K
A
I
E
Honey Bee
Apis mellifera
XP_395632
1292
149877
Y128
N
K
L
L
N
F
M
Y
F
Q
R
K
A
I
E
Nematode Worm
Caenorhab. elegans
O44518
1262
144995
R127
S
K
L
G
S
F
M
R
F
T
L
T
A
I
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5S2C3
1283
145467
R122
S
R
L
R
E
I
Q
R
W
Q
S
S
A
S
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
94
99.1
N.A.
97.9
85.8
N.A.
97.6
97.8
96
84.5
N.A.
62.6
65
51
N.A.
Protein Similarity:
100
100
94
99.2
N.A.
98
92.3
N.A.
97.8
98
97.2
91.6
N.A.
77.3
79.1
69.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
86.6
N.A.
100
100
100
73.3
N.A.
80
80
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
100
100
100
80
N.A.
86.6
86.6
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
79
% E
% Phe:
0
0
0
0
0
93
0
0
93
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
93
0
% I
% Lys:
0
93
0
0
58
0
0
0
0
0
0
72
0
0
0
% K
% Leu:
0
0
100
15
0
0
0
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
72
0
0
93
0
0
0
0
0
0
0
0
% M
% Asn:
22
0
0
0
29
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
93
0
0
0
0
8
% Q
% Arg:
0
8
0
8
0
0
0
15
0
0
86
0
0
0
0
% R
% Ser:
15
0
0
0
8
0
0
0
0
0
8
8
0
8
0
% S
% Thr:
65
0
0
0
0
0
0
0
0
8
0
15
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _